I thought I might add to this thread.
This was a study published back at the start at the year. In this study, the aurhors looked at the effect of stretching the trachea (tracheal traction) on airway collapsibility and surrounding tissue pressure in anaethetised rabbits. This study again confirms how important airway tension is in regards to airway collapsibility. It also goes into a bit of detail about tissue pressure. I have explained a bit about this in this thread (post 11).
viewtopic.php?t=22549&start=15
Sleep. 2007 Feb 1;30(2):179-86.Links
Tracheal traction effects on upper airway patency in rabbits: the role of tissue pressure.Kairaitis K, Byth K, Parikh R, Stavrinou R, Wheatley JR, Amis TC.
Ludwig Engel Centre for Respiratory Research, Department of Respiratory Medicine, Westmead Hospital, Hawkesbury Rd, Westmead, NSW, Australia.
kristinak@westgate.wh.usyd.edu.au
STUDY OBJECTIVES: To investigate the mechanisms via which lung volume related caudal tracheal traction decreases upper airway collapsibility. DESIGN: Acute physiological study. PARTICIPANTS: 20 male, supine, anesthetised, tracheostomised, spontaneously breathing, NZ white rabbits fitted with a sealed face mask. SETTING: N/A. MEASUREMENTS AND RESULTS: Upper airway extraluminal tissue pressure (ETP) was measured in the lateral (ETPlat) and anterior (ETPant) pharyngeal walls (pressure transducer tipped catheters). Graded traction was applied to the isolated upper airway (n = 17, 0-140 g). Subsequently, inflation and deflation was performed (with and without traction, 48 g, n = 13) with measurement of intraluminal pressure. Upper airway transmural pressure (PTM) was calculated (at closure and reopening) for both ETP sites (PTMlat and PTMant, respectively). A traction force of 144 g decreased ETPlat from 2.6 +/- 0.7 cm H2O (mean +/- SEM) to 2.1 +/- 0.7 cm H2O and ETPant from 1.1 +/- 0.4 cm H2O to 0.8 +/- 0.4 cm H2O (both P < 0.001). Increasing traction decreased closing and reopening pressures by 1.4 +/- 0.2 cm H2O for 48 g of traction (n = 13, P < 0.0001). In addition, 48 g of traction decreased ETPlat (at closure and reopening) by 0.2 +/- 0.05 cm H2O (P < 0.0001), and decreased ETPant by 0.5 +/- 0.1 cm H2O at closing pressure and 0.8 +/- 0.1 cm H2O at reopening (both p < 0.0001). Thus, for 48 g of traction, PTMlat (at closure and reopening) fell by 1.1 +/- 0.2 cm H2O and PTMant (reopening only) fell by 0.9 +/- 0.3 cm H2O (all P < 0.0001). CONCLUSIONS: Since tracheal traction decreased PTMlat and PTMant by a greater amount than ETPlat and ETPant, we conclude that the decrease in upper airway collapsibility mediated by lung volume related caudal tracheal traction is partially explained by reductions in ETP.