ResMed AirSense 10 Autoset just starts blowing at 10.1 pressure

Download, install and use SleepyHead.
Let's see what the machine actually says it is doing compared to what you see on the LCD screen it says it is doing.

viewtopic/t158560/How-to-post-images-for-review.html

and here to get SleepyHead
https://sleepyhead.jedimark.net/

Hopefully you have a SD card in the machine...if you don't go get one...any generic SD card will work.
It has to be in the machine while the machine is running to get any graphs.

I pulled up my AirSense MyAir app and it tells me how poorly my last two days have been (as it is just blowing air at 10.1 versus regulating). I have an SD card. Will sleepyhead disagnosis info that MyAir does not? Willing to try anything to get it working. Thank you for your advice!

I can't see what your MyAir is saying...and yes...SleepyHead offers a lot more than you can see on MyAir.
Did you look at the examples? Do you see anything like that at MyAir?

I suspect your machine is ailing for some reason and likely needs repair and/or replacement depending on how long you have owned it.
It's the weekend...can't get much of anything done about it right now anyway.

Just suggesting some stuff to help trouble shoot and rule out other potential factors before saying...you need a new machine.
Just on the off chance there is an easy fix...but we need to see what the machine says it is doing to be able to offer anything but a WAG...wild ass guess.
I don't like guessing when there is data available to at least make an educated guess.

Great points and no data like that on my air. I just need to find my card adapter as I have a new Mac. Thanks for your help and agree - nobody is around so need to try and figure out ideas. I have had machine for 3 1/2 years.

Appreciate your help!