avi123 wrote:SuddenlyWornOut45 wrote:
Eric
Comment,
Eric, when you're talking about taking medications and REMS (assuming also dreaming), then many sleep Docters are against taking sleep medication such as Zolpidem (generic Ambien) for sleep because it delays REMs. Would you regard it also as "
dumbing down your deep stages of sleep and preventing the CPAP from doing its full work" ? If you say yes, then what would be more important to you, to take the Zolpidem and be able to fall asleep or NOT to take the Zolpidem b/c of
"dumbing down" your deep stages or delaying your REMs?
First of all, I remember when Ambien first came out in the nineties. I had been diagnosed with major depression not too long in the late nineties when Ambien came out, but was not diagnosed with sleep apnea nor treated for it with CPAP. I enrolled in a study at the Medical University of South Carolina at Charleston in 1999 for rTMS for refractory major depression. A high tech study of the use of high tech magnet therapy for severe depression, it was being investigated back then as a possible replacement for ECT.
Anyway, I had to go off ALL psych meds for that study. I did not take klonopin or any sort of benzos back in those days, just anti-depressants and a lot of vitamins. I did take some anti-histamines OTC for insomnia back in those days. Looking back on it all, it was all VERY primitive, my "depression" treatment despite having access to some good quality psychiatric resources.
The one drug the MUSC Pdocs doing the rTMS would let us have during that study was Ambien. I was told by a top notch psychopharmacologist that "Ambien was a very good drug, it was very clean" I was told, specifically. Ambien is not like klonopin or other benzos nor like OTC benadryl for insomnia, ambien does not screw up slow wave sleep like benzos or benadryl or barbituates. Additionally, Ambien has a VERY short half life. Its in and out fast, which is good for your sleep architecture, supposedly.
I never had to take much of the stuff during that study. I took a little, not much. I found it to be a weak, subtle medication myself.
I later needed something much stronger for insomnia, BEFORE I was treated for OSA. Klonopin filled that need, but klonopin like all benzos is awful for suppressing deep stage sleep...especially slow wave sleep. Klonopin is why I rarely dream.
If it were me and I had to choose between taking ambien and being able to fall asleep and not taking ambien and having really chronic, severe insomnia, I'd choose the first. I'd take the ambien regular, because it is so weak compared to benzos. Its not even in the same class of drugs as benzos. Its classed as a "hypnotic." Its not useful for anxiety. It does not suppress slow wave sleep. It is a controlled substance, but if I remember right its the lowest control, like schedule 5 I think (have to verify that to be sure on that, its either schedule 5 or 4). The addiction potential is lower than benzos like klonopin and nothing even remotely in the same ballpark as something like prescription narcotic painkillers or prescription amphetamines like Ritalin.
Yeah, if I had to choose between having chronic insomnia and taking ambien at bedtime regular to knock me out, I'd choose ambien regularly. It's effect on sleep architecture is very weak. At big doses I suppose it could suppress respiratory drive (sedation of breathing muscles) some, but thats why you get an autopap or auto bipap.
Eric