Baseline for Desaturations and Flow rates

General Discussion on any topic relating to CPAP and/or Sleep Apnea.
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robysue1
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Re: Baseline for Desaturations and Flow rates

Post by robysue1 » Fri Dec 09, 2022 11:37 am

Tec5 wrote:
Fri Dec 09, 2022 10:42 am
robysue1 wrote:
Fri Dec 09, 2022 10:19 am
And, my guess is the breath that immediately precedes the first breath in the snippet is not only flow limited, but also quite likely part of the hypopnea.
The breath that was snipped (that apparently is associated with the a 0.04 flow limitation occurred 20 seconds before the hypopnea flag.
It's quite reasonable to use all the data in the 10 second interval for evaluating a hypopnea event, but to go back to an observation of data well in advance is unreasonable.

How far back in time do you folks want to go?
30 seconds usually far enough back. Sometimes it's worth looking at the whole minute before the event that you are wondering about. But I'll be honest, I typically prefer to see about 2 minutes back before the event occurred so that I get an understanding of the overall picture of what was going on at the time the event got flagged.
The the period this hypopnea flag should be examining should be from 01:09:10 to 01:09:20, not something that happened ten seconds sooner. (or do you disagree?)
Hypopneas can last more than 10 seconds. And I have found that the time flags on the hypopneas are usually far less accurate than the fact that something should be flagged. Sometimes the flag is also placed on top of the recovery breaths rather than at the end of the hypopnea itself. Why? I don't know, but programming these things is always going to still have some bugs where stuff doesn't always line up exactly correctly.

Here is a marked up screen shot from my own data of a hypopnea that is most likely a post-arousal false positive hypopnea, and it's easy to wonder why the H is drawn where Oscar draws it:

Image

Note that the H flag occurs after the first recovery breath. Why? I don't have the foggiest idea. Now the machine flags this as a 10-second hypopnea---we can see that when I use the mouse to hover over the hypopnea and Oscar "highlights" the breathing being flagged in this next screen shot of the exact same post-arousal hypopnea:

Image

But that the breath right before the "official start" of the hypopnea is clearly both flow limited and the smallest inhalation in the whole bit of displayed breathing, and in my opinion, the hypopnea starts with that inhalation rather than the 10-second window that is officially "flagged" as the hypopnea. Why isn't this hypopnea scored as a 15 second event with that first flow limited and smallest inhalation included in the area flagged as the hypopnea? I don't know.

(I guess an alternative theory might be that the hypopnea detecting algorithm takes more than ten seconds to decide)
Yes, it can take more than 10 seconds---most simply because a hypopnea can last more than 10 seconds. Moreover, scoring the end of the hypopnea is also a programming decision: How big does the recovery breath have to be? Do you need two of them? Those are also programming choices that only the Resmed programmers know the actual coding decisions that were made and only the Resmed programmers understand what kinds of things can creep into the flagging data when something barely meets the criteria.

It's important to remember: Resmed does not claim 100% accuracy in the flagging of events. They know there are false positives and false negatives. They know the flags don't always line up completely correctly. But statistically, the algorithms are good enough to have validity for trending data: If the machine AHIs are reasonably low for several weeks or months, it's a good bet that the actual number of real events that would be scored on an in-lab PSG are also quite low and the OSA is being well treated.

Questions I have for both you and Wondering1: What is the point of your analyzing the particular hypopneas in question? Are you trying to understand whether a particular hypopnea is a false positive or real? Or are you trying to make the case that the algorithms for scoring Hs are so inaccurate that we just shouldn't trust the things the machines flag at all? Or something else?

I ask, because neither one of you is willing to accept the answer: Programs based on sophisticated numerical analysis are never 100% accurate and errors can and do creep in when those algorithms are faced with data that is right at the edge of their abilities to "make decisions" based on programmed, numerical definitions. And that if you keep that point in mind, it's actually pretty easy to see why the machine could decide to flag the hypopneas you have presented in this thread.
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Re: Baseline for Desaturations and Flow rates

Post by robysue1 » Fri Dec 09, 2022 11:39 am

Tec5 wrote:
Fri Dec 09, 2022 10:59 am
robysue1 wrote:
Fri Dec 09, 2022 10:19 am
Resmed specifically says that it is used.
OK, I missed where Resmed specifically says that FL is used to establish a hypopnea.
Is that somewhere in this thread ?
Actually read the screen shots that Rubicon posted back in [url=viewtopic/t185583/Baseline-for-Desatura ... 0#p1428185]

It's in there in the fine print---you just need to look for it.
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Re: Baseline for Desaturations and Flow rates

Post by Tec5 » Fri Dec 09, 2022 12:04 pm

robysue1 wrote:
Fri Dec 09, 2022 11:39 am
Do you mean this:
Image
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Re: Baseline for Desaturations and Flow rates

Post by Tec5 » Fri Dec 09, 2022 12:10 pm

Rubicon wrote:
Fri Dec 09, 2022 11:12 am
After careful consideration, I have come to the conclusion that you are so fucking stupid as to boggle the imagination.
Of course, the second graders defense.
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Re: Baseline for Desaturations and Flow rates

Post by robysue1 » Fri Dec 09, 2022 2:42 pm

Tec5 wrote:
Fri Dec 09, 2022 12:04 pm
robysue1 wrote:
Fri Dec 09, 2022 11:39 am
Do you mean this:
Image
That's one of the pieces of fine print that indicate a Resmed machine is not going to score an H if there is not a flow limitation.

There's another piece of fine print in the second image posted by Rubicon back at viewtopic/t185583/Baseline-for-Desatura ... 0#p1428185

Can you find it as well?
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Re: Baseline for Desaturations and Flow rates

Post by Tec5 » Fri Dec 09, 2022 3:17 pm

robysue1 wrote:
Fri Dec 09, 2022 2:42 pm
There's another piece of fine print in the second image posted by Rubicon back at viewtopic/t185583/Baseline-for-Desatura ... 0#p1428185
Can you find it as well?
You mean this?
Image

Refers to obstructed, not flow limitations.

Which has now reminded me of a discussion here on this forum many months ago (that I'm just now trying to completely recall, but it was something that I filed away in my brain)

One of the forum members reported how some one of his family had fallen and broke a rib or something that caused to have pain whenever he took a breath.
Consequently his breathing tended to be haltingly attempted (that is he was incapable of taking a smooth inhalation)
Well, this showed up in his Flow Limitations graph as a marked change before and after injury. (which makes sense)
However, these flow limitations had more to do with pain than it had to do with obstructions in the airway.
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Re: Baseline for Desaturations and Flow rates

Post by zonker » Fri Dec 09, 2022 4:13 pm

Rubicon wrote:
Fri Dec 09, 2022 12:12 am


No really, what's your point?
oh, sorry. was just making a cryptic comment.

i'd post a cartoon but i can't seem to find anything appropriate.
people say i'm self absorbed.
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Re: Baseline for Desaturations and Flow rates

Post by robysue1 » Fri Dec 09, 2022 4:34 pm

Tec5 wrote:
Fri Dec 09, 2022 3:17 pm
robysue1 wrote:
Fri Dec 09, 2022 2:42 pm
There's another piece of fine print in the second image posted by Rubicon back at viewtopic/t185583/Baseline-for-Desatura ... 0#p1428185
Can you find it as well?
You mean this?
Image

Refers to obstructed, not flow limitations.
Flow limitations during sleep breathing are caused by obstructions in a person with sleep disordered breathing. And in this context, an "obstructed breath" is a breath with tell-tale characteristics (i.e. flow limitations) that indicate there is a high probability the airway is starting to collapse---if the person attached to the xPAP is sound asleep, has a problem with OSA, and is presumed to have no other significant issues affecting their sleep breathing.
One of the forum members reported how some one of his family had fallen and broke a rib or something that caused to have pain whenever he took a breath.
Consequently his breathing tended to be haltingly attempted (that is he was incapable of taking a smooth inhalation)
Well, this showed up in his Flow Limitations graph as a marked change before and after injury. (which makes sense)
However, these flow limitations had more to do with pain than it had to do with obstructions in the airway.
Just like an xPAP can't tell when we're asleep, an xPAP can't tell when we're in pain and when we're injured. It also can't tell if we're breathing through a stuffy nose. It can't tell if we're in the middle of an asthma attack. In other words, an xPAP can't tell why a person's inhalations are distorted.

Since an xPAP is designed to be used by people with OSA when they are sound asleep, the programs used to flag events are designed to flag distorted inhalations as flow limitations simply because for the average user on a typical night, the most likely cause of those flow limitations is an airway that is partially obstructed or partially collapsed rather than something like a broken rib. If the partial collapse is severe enough, the limitation in flow will show up in both peak height and in the shape of the inhalations---that's when an H gets scored instead of just a flow limitation. If the airway collapses completely, an OA is scored. (It's worth mentioning that I can quite easily fool an xPAP into scoring an OA when I'm wide awake and sitting up just by holding my breath---the particular way I seem to hold my breath seems to involve my epiglottis shutting off my wind pipe, and that causes the FOT algorithm to conclude the airway has collapsed.)

It's important to remember: All an xPAP has is the flow data. And whenever the flow data deviates significantly from what the shape of decent, regular sleep breathing looks like, the machine is going to start looking at the shape of the inhalations and comparing those shapes to shapes known to be associated with snoring and partially obstructed upper airways.

In developing the algorithms used to flag events, the engineers and programmers who design today's xPAP machines make use of extensive knowledge gleaned from numerically and statistically analyzing the flow data gathered on thousands (or hundreds of thousands) of PSGs that were scored by highly trained sleep technicians using all the data available on the PSG. The shapes the machines are programmed to call flow limitations, snoring, Hs, OAs, and CAs are known to have a high statistical correlation with specific types of sleep disordered breathing problems when those patterns occur during sleep.

Since xPAPs cannot tell when we're asleep and since they are designed to be used when we are asleep, the programmers have made the perfectly reasonable choice of assuming that most of the time an xPAP is used, the user is in fact asleep, and hence most of the time an xPAP detects patterns in the flow data that are statistically associated with sleep disordered breathing, there is a high probability that a sleep disordered breathing event may have occurred. And so the machine is going to flag something based on what it sees in that data. The choice of what to flag (OA, CA, H, RERA, flow limitation, snore) all depends on what the kind of sleep disordered breathing problem has a strong statistical correlation with the pattern the machine is detecting in the xPAPer's flow data.
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Re: Baseline for Desaturations and Flow rates

Post by palerider » Fri Dec 09, 2022 4:35 pm

robysue1 wrote:
Fri Dec 09, 2022 11:39 am
Tec5 wrote:
Fri Dec 09, 2022 10:59 am
robysue1 wrote:
Fri Dec 09, 2022 10:19 am
Resmed specifically says that it is used.
OK, I missed where Resmed specifically says that FL is used to establish a hypopnea.
Is that somewhere in this thread ?
Actually read the screen shots that Rubicon posted back in [url=viewtopic/t185583/Baseline-for-Desatura ... 0#p1428185]

It's in there in the fine print---you just need to look for it.
And THINK. But that's beyond the trolls.

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Re: Baseline for Desaturations and Flow rates

Post by robysue1 » Fri Dec 09, 2022 5:36 pm

palerider wrote:
Fri Dec 09, 2022 4:35 pm
robysue1 wrote:
Fri Dec 09, 2022 11:39 am
Tec5 wrote:
Fri Dec 09, 2022 10:59 am
robysue1 wrote:
Fri Dec 09, 2022 10:19 am
Resmed specifically says that it is used.
OK, I missed where Resmed specifically says that FL is used to establish a hypopnea.
Is that somewhere in this thread ?
Actually read the screen shots that Rubicon posted back in [url=viewtopic/t185583/Baseline-for-Desatura ... 0#p1428185]

It's in there in the fine print---you just need to look for it.
And THINK. But that's beyond the trolls.
Trolls gotta troll.

And in a later post, I think Tec5 thinks he's ever-so-clever pointing out that the phrase used in one Resmed snippet is "obstructed breath" instead of "flow limited breath." It's like Tec5 doesn't understand what synonyms are and why they get used even in technical English.
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Re: Baseline for Desaturations and Flow rates

Post by Tec5 » Fri Dec 09, 2022 5:54 pm

robysue1 wrote:
Fri Dec 09, 2022 5:36 pm
"obstructed breath" instead of "flow limited breath."

They are not synonymous, "obstructed breath" is a subset of "flow limited breath" (technically speaking)
I am neither a physician nor a lawyer, so DO NOT rely on me for professional medical or legal advice.