Pressure and the heart - any truth to this?

General Discussion on any topic relating to CPAP and/or Sleep Apnea.
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ozij
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Re: Pressure and the heart - any truth to this?

Post by ozij » Mon Sep 12, 2022 8:30 am

Rubicon wrote:
Mon Sep 12, 2022 4:37 am
Given enough CPAP you will crash anybody's BP. But again, normally that's more than a run-of-the-mill CPAP machine can produce.

Is that what the RN NP Whoever meant?
For those fortunate enough not have run into Contiuous Positive Air Pressure machines in a hospital setting (for themselves or for relatives): they are CPAP machines. But *not* the run of the mill CPAP machines we are using at home.

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lynninnj
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Re: Pressure and the heart - any truth to this?

Post by lynninnj » Mon Sep 12, 2022 8:45 am

ozij wrote:
Mon Sep 12, 2022 8:20 am
lynninnj wrote:
Mon Sep 12, 2022 6:01 am
I couldn’t tell. Maybe I could spend a long time reading it but it was very unclear to me as to whether those people on the study even have obstructive sleep apnea.
They did ...if you accept their diagnostic criteria and tools.
NEJM Paper wrote: Patients were recruited at 89 clinical centers in 7 countries; eligibility criteria included an age between 45 and 75 years, a diagnosis of coronary artery disease or cerebrovascular disease, and a diagnosis of moderate-to-severe obstructive sleep apnea. The diagnosis of moderate-to-severe obstructive sleep apnea, which was defined as an oxygen desaturation index (the number of times per hour during the oximetry recording that the blood oxygen saturation level drops by ≥4 percentage points from baseline) of at least 12, was established with the use of a home sleep-study screening device (ApneaLink, ResMed) and was confirmed by review of the data at a central core sleep laboratory
Sounds wishy washy.

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lazarus
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Re: Pressure and the heart - any truth to this?

Post by lazarus » Mon Sep 12, 2022 9:09 am

Maybe on topic, maybe not. But in case it interests anyone:

Because of my having a few nights of odd sensations in my hands and feet in the middle of the night, my primary and I decided to move my timing for my taking my BP meds to morning instead of just before bed. Seemed to do the trick.

Directly related to the topic of this thread? I have no idea, since I'm not aware of a way to take my BP while asleep for meaningful documented medical troubleshooting. But my personal noneducated theory as a patient is that the solution points to a possible correlation anecdotally in my case.

I am pretty sure the sensations were nothing neurological because I just passed an upper-extremity EMG test with flying colors. (Not a fun test for any who dislike electical shocks and having needles jammed into muscles of the arm and hand, by the way.)

The neurologist (who is also a sleep doc) doesn't like my personal theory on the few nights of simultaneous numbness in hands and feet during the night having been possibly cardiac-related and BP-med-timing related. She feels that if that were so the sensation would have been predominantly on the left side of my body, in her opinion. But, hey, she ain't no cardiologist, so if I EVER get anything like that sensation at night again, I will ask to see a cardiologist. For now, though, moving the timing of my meds seems to solve the issue for me, for whatever reason, and I have no cardiac symptoms at all during the day. So I'll choose something else to be concerned about.

Hope this out-there fringe post doesn't get me put on anyone's end-sig no-fly list. Not my intention to hijack. Not this time, anyway.

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SleepGeek
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Re: Pressure and the heart - any truth to this?

Post by SleepGeek » Mon Sep 12, 2022 10:36 am

lazarus wrote:
Mon Sep 12, 2022 9:09 am
I decided to move my timing for my taking my BP meds to morning instead of just before bed. Seemed to do the trick.
Curious to learn the name of a BP med taken before bed?
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lazarus
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Re: Pressure and the heart - any truth to this?

Post by lazarus » Mon Sep 12, 2022 10:52 am

"All"?

https://www.nature.com/articles/s41569-019-0306-y

"Participating primary care physicians were allowed to prescribe without restriction any BP-lowering medication approved by the Spanish Agency of Medications and Health Products for once-daily dosing from any of the five listed recommended therapeutic classes."

https://academic.oup.com/eurheartj/arti ... 65/5602478

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Re: Pressure and the heart - any truth to this?

Post by Pugsy » Mon Sep 12, 2022 11:07 am

SleepGeek wrote:
Mon Sep 12, 2022 10:36 am
lazarus wrote:
Mon Sep 12, 2022 9:09 am
I decided to move my timing for my taking my BP meds to morning instead of just before bed. Seemed to do the trick.
Curious to learn the name of a BP med taken before bed?
Hmmm...how about
Losartan 50 mg

Had been taking Losartan 50/HCTZ 25 combination every morning....one pill...for many years.
Getting not always consistent results but not horrible results. Mainly systolic wasn't very stable or as stable as was desired.
So doc decided to split it up...HCTZ 25 in the AM and the Losartan 50 in the evening about a month ago.

Same dosage of meds but split up...
Systolic is now 20 to 30 points lower.
Diastolic was never a huge concern but it seems to have dropped about 10 points as well.

There are probably other examples.

Moral...don't assume that just because some sort of medical treatment "has always been done this way" that it won't ever change to a new way of doing something.

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SleepGeek
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Re: Pressure and the heart - any truth to this?

Post by SleepGeek » Mon Sep 12, 2022 11:15 am

Pugsy wrote:
Mon Sep 12, 2022 11:07 am
Hmmm...how about
Losartan 50 mg
Well TY.
Since I don't take it and never heard of it I thought I'd learn something.

Are you sure Losartan 50 mg is what he is taking?
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Re: Pressure and the heart - any truth to this?

Post by lazarus » Mon Sep 12, 2022 11:39 am

Me? Yep, losartan, but double that and with an amlodipine chaser.

My understanding is that most docs used to tell everyone to take BP meds upon waking in order to make it a dependable routine that patients were unlikely to forget. But that decently sized and constructed study seems to have changed minds on that earlier recommendation for a number of up-to-date practitioners around the world. My previous primary put more stock in that study than my present one, though. Insurance forced me to switch my primary a few years ago, although I still consult with my previous primary off the books now and then.
Last edited by lazarus on Mon Sep 12, 2022 11:43 am, edited 1 time in total.

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Pugsy
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Re: Pressure and the heart - any truth to this?

Post by Pugsy » Mon Sep 12, 2022 11:41 am

SleepGeek wrote:
Mon Sep 12, 2022 11:15 am
Pugsy wrote:
Mon Sep 12, 2022 11:07 am
Hmmm...how about
Losartan 50 mg
Well TY.
Since I don't take it and never heard of it I thought I'd learn something.

Are you sure Losartan 50 mg is what he is taking?
Sorry....my mind and fingers didn't connect well.

I should have said
Pugsy wrote:
Mon Sep 12, 2022 11:07 am
I Had been taking Losartan 50/HCTZ 25 combination every morning....one pill...for many years.
Wasn't a he at all...it was a me, myself and I that I was talking about.

I got the bottles of both/all to prove it. I always know exactly what I take at all times. I am not senile yet.
Though I will admit that the evening dose sure took a few nights to get used to doing after so many years of a morning dose alone.

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Re: Pressure and the heart - any truth to this?

Post by SleepGeek » Mon Sep 12, 2022 11:49 am

Pugsy wrote:
Mon Sep 12, 2022 11:41 am
Wasn't a he at all...it was a me, myself and I that I was talking about.
Its clear what you were taking but my question was addressed to lazarus
SleepGeek wrote:
Mon Sep 12, 2022 10:36 am
lazarus wrote:
Mon Sep 12, 2022 9:09 am
I decided to move my timing for my taking my BP meds to morning instead of just before bed. Seemed to do the trick.
Curious to learn the name of a BP med taken before bed?
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lazarus
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Re: Pressure and the heart - any truth to this?

Post by lazarus » Mon Sep 12, 2022 12:18 pm

And for the record, I think HIPAA may prevent Pugsy from telling anyone what meds I take, but she has my full permission to give out my credit card number and mother's maiden name. Until she's senile, anyway. Which she certainly ain't that. (Yet.)

Just kidding. Sorry for any part I played in the minor misunderstanding.

My opinion, for which I have zero proof or support, is that PAP was already letting ME do the nocturnal BP-dip thing well enough, so MY taking my increased BP meds at night wasn't best for ME. That said, I personally respect the study, even though just one, which points at least to considering taking those meds before bed, for most.

Point made. Off to find another thread to hijack.

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SleepGeek
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Re: Pressure and the heart - any truth to this?

Post by SleepGeek » Mon Sep 12, 2022 3:14 pm

lazarus wrote:
Mon Sep 12, 2022 12:18 pm
My opinion, for which I have zero proof or support, is that PAP was already letting ME do the nocturnal BP-dip thing well enough, so MY taking my increased BP meds at night wasn't best for ME.
My thoughts exactly. I would think that would be for someone not currently being treated for OSA.
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Re: Pressure and the heart - any truth to this?

Post by chunkyfrog » Mon Sep 12, 2022 10:17 pm

I take metoprolol at bedtime--as suggested by my cardiologist.
I switched my baby aspirin from morning to bedtime years ago.
It seemed to have a better result.

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Re: Pressure and the heart - any truth to this?

Post by palerider » Tue Sep 13, 2022 12:16 pm

GearChange wrote:
Sun Sep 11, 2022 9:33 pm
earlvillestu wrote:
Thu Sep 08, 2022 7:00 am
First, some background, and then a question.



I've done quite a bit of reading about CPAP, and I've never come across that claim. Is there any truth to it?
=
I would ignore Rubicon's Remarks in their entirety.
yes, ignore one of the most knowledgeable people on the forum and listen to someone with a severe and irrational bias.

THAT makes "sense".

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Re: Pressure and the heart - any truth to this?

Post by babydinosnoreless » Tue Sep 13, 2022 10:27 pm

If I am correct grumpy here was lucy here, Lazarus was JNK. Zonker, PR , Froggie and Pugsy have stayed the same but whats really driving me crazy is who was rubicon?