That's misleading. The parent drug, lisdexamfetamine, metabolizes pretty quickly into l-lysine and dextroamphetamine. That's probably where your 4-5 hour number came from. But that's only half the story. The half-life of dextroamphetamine is about 12 hours in healthy adult volunteers. Add that to the 1-4 hours it takes for the body to convert lisdexamfetamine to dextroamphetamine, and you get the full picture. If you're a fast metabolizer, your half-life might be 9-10 hours instead of 12-13.jimmye4golf wrote: ↑Wed Apr 17, 2019 11:40 amI googled Vyvanse half life and it says 4.3 - 5.5 hours. I still plan on going a weekend without it just to see. The only bad part of that is when I do have a 2 day weekend one day is mostly my younger kids soccer all day and Sunday is work around the house after sleeping in and sometimes a nap if the weather sucks.
Finding an ADHD treatment with a shorter half-life may or may not be an option for you, but it's definitely worth discussing with your ADHD doctor and possibly also your pulmonologist or sleep medicine provider.
