Magnesium is Effective and Safe Treatment for Depression

It seems many that suffer from apnea also suffer from depression and anxiety like symptoms. Perhaps magnesium supplements would be useful in treating these symptoms. (Without citation: Magnesium is also thought to be useful in treating PLMD)

The story:Tarleton Study Finds Magnesium is Effective and Safe Treatment for Depression http://www.med.uvm.edu/com/news/2017/06 ... depression

The study: Role of magnesium supplementation in the treatment of depression: A randomized clinical trial
http://journals.plos.org/plosone/articl ... ne.0180067

Daily supplementation with 248 mg of elemental magnesium as four 500 mg tablets of magnesium chloride per day leads to a significant decrease in depression and anxiety symptoms regardless of age, gender, baseline severity of depression, or use of antidepressant medications.

Note: The supplementation used in this study was Magnesium Chloride not Magnesium Oxide which is the most common over-the-counter compound of magnesium. Various sources cite magnesium oxide as providing poor bioavailability of elemental magnesium.

FYI I think Magnesium GLycinate is a well-absorbed and well-tolerated formulation vs mag oxide which can cause diarrhea.

Jay Aitchsee wrote: Various sources cite magnesium oxide as providing poor bioavailability of elemental magnesium.

magox is the primary active ingredient in milk of magnesia... so... yeah, it's the least absorptive of the forms of magnesium... don't buy it unless you need to .... help move things along... :cough:

Jay, even before I started chemo, a very small amount always caused an adverse reaction. I found it very frustrating that my body wasn't accepting something I felt I needed do badly.

Last month, due to frustrations with constipation, I tried a minuscule amount. Felt great initially but about three hours later, I felt very hyper and had to eat junk food to quell the reactions.

On to looking at magnesium food sources.

xxyzx wrote: if it is effective then why are there so many other things to treat depression

BIG PHARMA

xxyzx wrote:

Jay Aitchsee wrote:It seems many that suffer from apnea also suffer from depression and anxiety like symptoms. Perhaps magnesium supplements would be useful in treating these symptoms. (Without citation: Magnesium is also thought to be useful in treating PLMD)

The story:Tarleton Study Finds Magnesium is Effective and Safe Treatment for Depression http://www.med.uvm.edu/com/news/2017/06 ... depression

The study: Role of magnesium supplementation in the treatment of depression: A randomized clinical trial
http://journals.plos.org/plosone/articl ... ne.0180067

Daily supplementation with 248 mg of elemental magnesium as four 500 mg tablets of magnesium chloride per day leads to a significant decrease in depression and anxiety symptoms regardless of age, gender, baseline severity of depression, or use of antidepressant medications.

Note: The supplementation used in this study was Magnesium Chloride not Magnesium Oxide which is the most common over-the-counter compound of magnesium. Various sources cite magnesium oxide as providing poor bioavailability of elemental magnesium.

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if it is effective then why are there so many other things to treat depression

I'm not saying it's effective, but profit and ad's drive the market, follow the money!

Good News, all these "So called Studies" at least provide paychecks for the "Homeless Scholars", at least someday they may be able to move out of their parents basement! I doubt if it will ever be enough to pay off the loans. Jim

Jay Aitchsee wrote:

xxyzx wrote: if it is effective then why are there so many other things to treat depression

BIG PHARMA

+100

I think the right dose of the right Mag. may help some people with minor depression to feel somewhat better, but I don't believe it's going to do the same job as prescription meds in major depression by a long shot. Helpful, but not a real cure. I've taken it for a long time for other reasons (not plumbing related tho' it does help to keep things moving), but I wouldn't depend on it as a 'full time' depression med.

xxyzx wrote:i merely wonder if it is so red hot why do people shell out for Rx that cost $$$$$ vs ccccc

Indeed!

Julie wrote:I've taken it for a long time for other reasons

Not depressed, then? Maybe it's working!

xxyzx wrote:logical fallacy like saying that when we dance every afternoon it keeps the elephants away at nightwe have not seen an elephant at night since we started the daily dancing

But what about the giraffes?

I got my magnesium levels checked. Rock bottom. I had all sorts of weird things going on. I've been supplementing for 18 months (malate, glycinate). Magnesium is super important; without it vitamin D metabolism is shot as well. For brain health, both psychiatric and neurological.

I have one neurologist who still thinks supplements are useless. Most docs don't even test for it (it's not a great test; if you come up low you're REALLY low, but normal doesn't necessarily mean in a good place because blood levels are maintained at a constant level). This is why all the scary stuff is prescribed instead. Doctors aren't educated, yet. I have two now that are though so thinks are improving.

In a crisis, I think the other meds have their place, but also folks should start addressing deficiencies,just in case eventually the meds won't be necessary.

xxyzx wrote:Office of Dietary Supplements

Thanks for that Reference. Lots of good information there. Why we need it, effects of deficiency, difficulty in assessing magnesium level status, etc.
A few cherry picked points to pique interest:

https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/ wrote:
Dietary surveys of people in the United States consistently show that intakes of magnesium are lower than recommended amounts.

Very large doses of magnesium-containing laxatives and antacids (typically providing more than 5,000 mg/day magnesium) have been associated with magnesium toxicity

Tolerable Upper Intake Levels (ULs) for Supplemental Magnesium [1]
19+ years 350 mg

Jay Aitchsee wrote:

xxyzx wrote:logical fallacy like saying that when we dance every afternoon it keeps the elephants away at nightwe have not seen an elephant at night since we started the daily dancing

But what about the giraffes?

That's Silly, Everyone knows Giraffes don't mind dancing! Jim