xxyzx,
I went back and searched duloxetine and looked for breathing problems. I checked 4 different web sites. None of them mentioned breathing problems. Why would you search a trade name when the medication was prescribed under the generic name. They are not always totally the same. So you are not totally wrong just very misleading in your ignorance of reality.
Plus your references are crap. They do not qualify as facts. They qualify as rumors.
Sudden jump in AHI with new medication
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WickedLoki
- Posts: 40
- Joined: Sat Aug 20, 2016 2:27 pm
Re: Sudden jump in AHI with new medication
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Last edited by WickedLoki on Sun Jul 09, 2017 12:58 pm, edited 1 time in total.
Re: Sudden jump in AHI with new medication
Some complicated people (waves hand) have decreased respiratory drive with CNS depressants. You see it more commonly with opiates.
In the wiki article for duloxetin and others, there is a contraindication:
"Central nervous system (CNS) acting drugs: given the primary CNS effects of duloxetine, it should be used with caution when it is taken in combination with or substituted for other centrally acting drugs, including those with a similar mechanism of action."
So for some with certain preexisting chronic conditions that affect the CNS, even if they are not on another CNS acting med ... a decrease in respiratory drive happens.
Some complicated people (waves hands again) have increased OSA if they take muscle relaxers. I can't even take OTC robaxecet without boosting my CPAP pressure.
This may be uncommon, but it absolutely happens. Never say never. Humans are complex.
In the wiki article for duloxetin and others, there is a contraindication:
"Central nervous system (CNS) acting drugs: given the primary CNS effects of duloxetine, it should be used with caution when it is taken in combination with or substituted for other centrally acting drugs, including those with a similar mechanism of action."
So for some with certain preexisting chronic conditions that affect the CNS, even if they are not on another CNS acting med ... a decrease in respiratory drive happens.
Some complicated people (waves hands again) have increased OSA if they take muscle relaxers. I can't even take OTC robaxecet without boosting my CPAP pressure.
This may be uncommon, but it absolutely happens. Never say never. Humans are complex.