I bought this device a few years ago and used it with on my Win7 computer. The reports it presented were virtually identical to the one I got from an official sleep clinic study, SPO2 section. I bought a Win10 computer last year and found it incompatible with the oximeter as many other forums on the web also claimed. Lots of frustration from purchasers of the CMS-50D+.
BIG NOTE: the USB-looking cable that comes with it IS NOT Strictly A USB CABLE, it just looks like one. It's a USB to serial in one cable. Do yourself a BIG favor and label it as only compatible with the CMS-50D Plus oximeter and no USB device so you don't lose or misuse it. Shame on them for making it look like a normal USB cable. It ONLY WORKS with the oximeter. I lost the cable from the 1st one I bought (probably got mixed up with my older USB mini cables and disappeared) so I had to by another CMS-50D + just to get the cable!
Anyway, go here
http://www.pulseoxstore.com/content/manuals-downloads
to get both the SPO2Review and SPO2Assistant downloads (V1.5 and V 2.4 respectively). Install and you'll probably find they work with the latest Win10 update.
I have moderate success at using rechargeable AAA NMiH batteries but can get (maybe) one night use before recharge as the NMiH voltage (1.2v vs 1.5v) is too low. I can use a recharger to get one more night of use out of alkaline batteries. I use a lightly wrapped rubberband to squeeze my finger a little tighter on the oximeter placed my non-dominant hand to keep the device on through the night. I have also used a Velcro strap around my wrist with a small ribbon connected to the oximeter to keep it on.
Great product for following how effective your CPAP machine is (try with and without CPAP to convince yourself) and whether you need additional help like tape across your mouth as I do

I am presently working on a CNAP solution (you figure it out
