Fractured sleep, Ambien, dial wingin' and other things

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by robysue » Tue Mar 04, 2014 8:30 am

SleepingUgly wrote:Have you tried Sonota instead of Ambien? It is shorter acting and might leave you less hung-over.
Back in the First War on Insomnia, I was switched to Sonata specifically because it is shorter acting. Unfortunately, my reaction to Sonata is unusual:

Within 5-10 minutes taking the Sonata, I feel "drugged" as in tired and fuzzy brained, but also keyed up rather than relaxed and sleepy. And the keyed up feeling usually prevents me from actually falling asleep. The feeling after taking Sonata is not at all sleep inducing for me: I typically lie in bed feeling really weirded out for 30-40 minutes or more) until the drugged feeling starts to wear off, at which point I'll then be able to get to sleep---if the aerophagia has not kicked in.

At least the Ambien does not key me up or weird me out---it actually does allow me to feel sleepy in a way that resembles a normal feeling of sleepiness.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by robysue » Tue Mar 04, 2014 8:40 am

John Chowder wrote:Hi robysue,

So sorry you are suffering from insomnia Have you ever tried natural remedies? I've had success with melatonin, 5-htp, and magnesium in the past. I've also used a natural pill called Alteril that's worked pretty well.

Hope you can get this solved!
Melatonin: I tried 1 mg tabs (smallest I could find) taken at bedtime during the First War. It may have marginally reduced the number of middle of night wakes, but it also seriously increased the TMJ problems. I also tried 1 mg tabs taken 6 hours before bedtime at the suggestion of my current sleep doc to try to get the delayed sleep phase problem better under control. It helped a bit to stabilize the bedtime at before 2:30, but again TMJ problems started to emerge and I quite taking it for that reason.

Magnesium: As part of the migraine meds I'm taking 500mg of Magnesium daily. I take 250 mg twice a day---once with breakfast and one near bedtime.

I have not tried 5-htp and I have not heard of Alteril.

I know I'm sounding like a broken record. But drug sensitivity is a huge issue for me. Part of it is size: I've never understood why "adult doses" for medication do not take into account the patient's physical size: At 110 lbs, I'm prescrribed the same dose of medication that my 175 lb husband is prescribed. But part of my problem is that I also am just plain sensitive to stuff that others don't seem to be all that sensitive to.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by 49er » Tue Mar 04, 2014 8:54 am

I know I'm sounding like a broken record. But drug sensitivity is a huge issue for me. Part of it is size: I've never understood why "adult doses" for medication do not take into account the patient's physical size: At 110 lbs, I'm prescrribed the same dose of medication that my 175 lb husband is prescribed. But part of my problem is that I also am just plain sensitive to stuff that others don't seem to be all that sensitive to
Roby Sue,

Sorry for this OT response but drug sensitivity is a huge issue for me also so no, you're not sounding like a broken record. Getting doctors to understand that is a whole other issue. They look at you like you're from Mars when you express those concerns.

My heart goes out to you and I hope you can resolve the problem.

49er

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by avi123 » Tue Mar 04, 2014 9:33 am

SleepingUgly wrote:Have you tried Sonota instead of Ambien? It is shorter acting and might leave you less hung-over.
Sonata vs Ambien:

http://www.webmd.com/sleep-disorders/in ... edications


Listed below are some drugs that can be used to treat insomnia.


Ambien (zolpidem): The original version of Ambien works well at helping you get to sleep, but some people tended to wake up in the middle of the night. Ambien CR is an extended release version. It helps you get to sleep within 15 to 30 minutes, and the new extended release portion helps you stay asleep. You should not take Ambien or Ambien CR unless you are able to get a full night's sleep -- at least 7 to 8 hours. The FDA has approved a prescription oral spray called Zolpimist, which contains Ambien's active ingredient, for the short-term treatment of insomnia brought on by difficulty falling asleep. The FDA requires that these drugs are offered in lower doses for women. Women clear the drugs from their systems more slowly than men and the agency says blood levels of the drugs could still be high enough the following morning to affect activities that require alertness, such as driving. The FDA says doctors should consider the lower dose for men too.


Sonata (zaleplon): Of all the new sleeping pills, Sonata stays active in the body for the shortest amount of time. That means you can try to fall asleep on your own. Then, if you're still staring at the clock at 2 a.m., you can take it without feeling drowsy in the morning. However, if you tend to wake during the night, this might not be the best choice for you.

More stuff that Sue knows about:

{set Window on only 100% zoom}

Image

Image

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by 49er » Tue Mar 04, 2014 1:51 pm

Hi robysue,

Found this on the blog of someone who suffered severe insomnia from psych med withdrawal and became so sensitive to everything that she could only take this one supplement for sleep which is Lactium.

http://beyondmeds.com/2013/02/05/help-for-insomnia/

Amazon has it here, http://www.amazon.com/gp/product/B0017O ... B0017O95SQ, under the name of Women's anti stress tablets which is simply a bunch of marketing BS and nothing more. I think this is about the cheapest price but of course, double check to make sure.

Just so you know, it never worked for me but many people swear by it on the AD withdrawal board that I visit alot.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by robysue » Wed Mar 05, 2014 12:55 am

When I finally got around to looking at today's data, it confirmed what I already knew: While I was in bed for almost 7 1/2 hours, I didn't get much real sleep. During the night I had at least 9 wakes (and possibly as many as 11 or 12 distinct wakes). And there were several periods of restlessness with less than 30 minutes of sleep between wakes.

The beginning of the night was rougher than I thought. At the first real wake of the night, I thought I had fallen asleep the first time about 15 minutes after going to bed (and the wave flow backs this up), and I remembered waking up pretty early in the night with aerophagia and hitting the ramp button and the on-off button to see if I could relieve some of the tummy problems and I also remembered this wake was a "long one" in that I guessed it took about 10-15 minutes to get back to sleep. I didn't bother looking at the clock in an effort to try to figure out how long I had been asleep before that first wake. When I downloaded the data into Sleepy Head, I was a bit shocked to find out that first wake happened about 20 minutes after I first fell asleep.

In fact, the first 4 1/2 hours of the night was rough. There were a lot of wakes during that time---and many of the wakes were after 30 minutes or less of sleep since the last wake.

The longest restless period lasted for almost an hour. Between 3:00 and 3:50 I hit the ramp button or the on-off switch for a grand total of 4 times, with the longest time between on-off cycles being a bit more than 15 minutes. My memory of this period is of repeatedly falling asleep for a few minutes only to rewake because the pressure was getting to my stomach and hitting the ramp or turning the machine off and on and hitting the ramp because of discomfort from aerophagia. Whatever sleep I got during that hour was in awfully short spurts, but because I kept managing to fall asleep (briefly) I didn't get out of bed. Perhaps I should have.

The sleep at the end of the night was not terribly fragmented: I did get two periods of (almost) 1 1/2 hours of sleep between wakes at the end of the night with 10-15 minute restless period between them. But I also had a pretty significant amount of migraine aura during that wake, and when I got up after the second 1 1/2 hour period of sleep, I was exhausted, the migraine aura was still around, and my stomach was bloated and very rigid from the aerophagia. The migraine aura got extremely bad over breakfast and even triggered some nausea, which is very unusual for my migraines. I did take a Maxalt (eventually), which seemed to minimize the migraine pain, but did not eliminate it. It also did not eliminate the aura problems or the nausea. Needless to say, I've felt rather shitty all day long and didn't manage to get a damn thing done.

As I stated at the beginning of this thread, my AHI has been running a bit higher than normal for several weeks now while running in Auto BiPAP mode and the insomnia had been starting to get a bit worse. So three nights ago I'd decided to see whether I might do better on fixed pressure; I had intended on leaving the machine at 8/5 for a week or so to see if fixed pressure might help either the AHI or the growing number of wakes.

Well, with fixed pressure, the AHI is way, way down, but the aerophagia is way, way up. And last night was an awful reminder of the agony I experienced night after night during my first six months of PAPing. And today I woke up with both severe aerophagia and migraine symptoms. The migraine aura got extremely bad over breakfast and even triggered some nausea, which is very unusual for my migraines. Needless to say, I've felt rather shitty all day long and didn't manage to get a damn thing done.

So for now, I've decided to abandon the trial of fixed BiPAP pressures: Last night's experience has unfortunately reminded me my stomach just can't seem to tolerate 8/5 while I'm still awake. And between the uncomfortableness of the 8/5 pressures and the aerophagia, the sensory overload last night triggered the worst migraine I've had in several months. And I think the slow, but steady increase in pressure during the ramp period(s) may be more disruptive for getting and staying asleep than the changes in pressure caused by the Auto algorithm are.

It's almost 2:00. I'm pretty tired and I am just now getting a bit sleepy, but I'm also pretty keyed up about just how bad last night was. So tonight I'm taking an Ambien as well as switching the machine back to my old Auto range of min EPAP = 4; max IPAP = 8. I'm sure the AHI will skyrocket relative to the last three nights, but some real sleep with a higher AHI beats waking up all night long with aerophagia and waking up in the morning with the kind of migraine I've had all day long.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by Country4ever » Wed Mar 05, 2014 7:09 am

I'm not sure what your settings are, but I woke up all night long on the autopap settings. I changed it to straight cpap, and would sleep so much better, and uninterrupted.
However in the past year (I've been on cpap for 7 years), I started waking up alot during the night again. I wonder if that's "normal" for aging?

I have alpha wave intrusion.......which means just as you're reaching a lower stage of sleep, your brain wakes you up. There's a med for this, but I don't think it has good results. My doc really didn't want to put me on it.
Also.........never eat in the evening. When your GI tract is awake............so is your brain.
How's your pain at night? I have leg pain, and sleep so much better if I take acetaminophen before bed.

I think some of us.....women especially......are very light sleepers. It dates back to us having to guard the cave at night, while the men were totally unconscious from catching that wooly mammoth.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by Pugsy » Wed Mar 05, 2014 8:26 am

robysue wrote: switching the machine back to my old Auto range of min EPAP = 4; max IPAP = 8. I'm sure the AHI will skyrocket relative to the last three nights, but some real sleep with a higher AHI beats waking up all night long with aerophagia and waking up in the morning with the kind of migraine I've had all day long.

Sometimes we just have to make compromises in an effort to get decent quality sleep and it's not like your AHI is in double digits when you do but even if it was over 5 all the time it would beat not getting any decent sleep due to the aerophagia and stuff. I am fortunate in that I haven't had many nights where aerophagia was an issue but I have had it on occasion so bad that I was physically ill the next day pretty much well into evening...so I understand. If I had to choose between maybe some less than stellar AHI reports and the aerophagia problem....the less than stellar AHI would win out.

First and foremost we have to get to sleep and stay asleep as best we can. Your sleep is already so fragile that we simply don't have any extra room to have aerophagia mucking up things.

I really don't have anything new to offer as an idea to help you sleep longer/better without the awakenings. You have already tried everything I would have thought of and then some things I didn't think of.
At the first of my therapy I also had multiple awakenings (20 to 30 a night) due to pain when I would move in bed. It reeks havoc on the sleep quality and we just have to have some decent sleep quality to have any chance of feeling decent the next day. My doctor and I compromised on meds to help me "sleep through the pain" and help reduce the pain..it's the only way I can get past those multiple awakenings. Even now I still have a few but nothing like I used to have.

And I understand that the Ambien causes a bit of a fog in the AM. I get it too if I take Ambien and especially if I take it too late. I can't imagine the fog I would have if I took it as late as you do. And I cut my pills down to about a 1/3 of a 10 mg dose. I can't seem to get them down any smaller. I don't take it every night though. It's saved for special occasions.

The mind can be a wonderful thing except when we want to shut it off so we can sleep...

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by robysue » Wed Mar 05, 2014 9:18 am

Going back to my old auto range last night and taking the Ambien did lead to fewer wakes (4 or 5 instead of about 10), and much, much less aerophagia. The AHI was only 2.1, which is a bit less than it's been running in Auto mode recently, but twice as high as what I was getting in fixed BiPAP mode. And I while I was in bed for only 5.5 hours, I think I was actually asleep for 4.8 or 4.9 hours, for a sleep efficiency of about 88% (as compared to getting 5.5 hours of fractured sleep in a 7.1 time-in-bed period the night before, for a sleep efficiency of about 78%). There's Ambien hangover to deal with, but today it's not too bad.
Country4ever wrote:I'm not sure what your settings are, but I woke up all night long on the autopap settings. I changed it to straight cpap, and would sleep so much better, and uninterrupted.
This idea was what lead to me deciding to try fixed pressures for a few days. I had hoped that the fixed pressures might lead to both a lower AHI and a bit more sleep continuity without too much of an increase in the areophagia. But, for me, the experiment failed because my stomach could not handle the low fixed pressures of 8/5 while awake, and hence I had to use the ramp, and I suspect the small, but steady increase in pressure during the ramp was enough when I was awake to cause additional wakefulness rather than allowing me to get to sleep more readily.
However in the past year (I've been on cpap for 7 years), I started waking up alot during the night again. I wonder if that's "normal" for aging?

I have alpha wave intrusion.......which means just as you're reaching a lower stage of sleep, your brain wakes you up. There's a med for this, but I don't think it has good results. My doc really didn't want to put me on it.
Some increase in wakefulness during sleep is age related; some of that age related increase is probably due to things like your alpha wave intrusions, which can be caused by things like pain.

In my case I believe that I do NOT have unreasonable expectations about what my sleep can or should be like. The conversations with my sleep doc seem to confirm this. I do not expect to eliminate all middle-of-the-night wakes. And I do not expect to suddenly increase the amount of sleep I actually get to 8 "solid" hours.

My goals are much less lofty, but much more realistic: I know that if the number of wakes is limited to 2-4 post-REM wakes and if the longest wake is 10 minutes or so and if I get 6.5-7 hours of sleep in a 7-7.5 hour time-in-bed window (i.e. my sleep efficency is at least 90%), and the AHI < 2.5 or so, then I'll feel and function pretty good all day long.

But right now? There are too many wakes for them to all be post-REM, too many of the wakes are 10 minutes or longer, my total sleep is less than 6 hours too much of the time, my sleep efficiency is less than 90% too much of the time, and the AHI is > 3 much more than it used to be. Any one of these things can adversely affect how I feel and function; and when lots of them happen all at the same time, I start to feel pretty bad pretty quickly.

Also.........never eat in the evening. When your GI tract is awake............so is your brain.
Eating supper late is occasionally an issue, but I've learned to watch both what and when I eat relative to my extremely late bedtime. On the days where I was attempting my fixed BiPAP pressures experiement, I made sure that supper was early enough and light enough to not be a potential aerophagia trigger. But the aerophagia still returned with a vengence.

[qyuote]How's your pain at night? I have leg pain, and sleep so much better if I take acetaminophen before bed.[/quote]Pain from injuries was a factor is aggravating the most recent round of insomnia back in October and November---it may even have been a significant trigger. In late October while out on one of my 3.5 miles walks, I fell hard enough to skin both knees and elbows, and landed mainly on my left knee twisting it slightly. After limping home the left knee was hurting pretty bad. I continued favoring the knee, but like a fool, I didn't go in to the doc's to have it checked out (it was NOT as painful as the MCL injury to the right knee back in Feb. 2012). But the limping around triggered severe back pain and I woke up over Veteran's Day weekend with the worst back pain I've ever had (except for back labor) and no matter what I did, I could not find a position that eased the pain at all. That sent me to the PCP, who ordered x-rays for both the left knee and the lower spine. The left knee x-ray showed nothing of interest, the lower spine x-ray showed some arthritis. And so the PCP sent me on to an orhopedic specialist who has a strong preference for PT as the first line of treatment for back pain.

Throughout most of November, I was taking a fair amount of NSAID pain relievers for the back (and knee) pain. The OTC ibuprophen was not making much of a dent, but did allow me to sleep at least fitfully. After seeing the PCP, he prescribed a stronger NSAID, which I don't recall the name of. The prescription NSAID did provlde enough pain relief where I could sleep half-way decently and function during the daytime without feeling like I was in excruciating back pain.

I started PT for the back in early December. The left knee was still bothering me, but the back was bothering me much much more. The physical therapist concentrated mostly on the back pain, but he also paid attention to the knee and we did a bit of stuff for it. By the beginning of February, the back was feeling better than it's felt in years---as in far better than it felt before the fall in October. But the knee was continuing to give me quite a bit of trouble. The physical therapist told me to make sure I mentioned this at the already scheduled appointment with orthopedic doctor earmarked as a post PT follow-up for the back pain.

At the Feb appointment, the orthopedic doctor spent a little bit of time checking out the back (since I was reporting no back pain) and quite a bit of time checking out the left knee (since it was still painful). He suggested an ultrasound of the knee with the possibility of a steroid shot (or two) based on what the ultrasound showed. The ultrasound was scheduled for the following week, and it did show two inflamed bursas and he did the steroid shots at that same appointment. He suggested waiting a couple of weeks to see whether the shots helped the knee stat to heal before starting PT for the knee. The shots did reduce the pain quite a bit---it's virtually pain free now. But the left knee is still quite a bit weaker than the right one (and recall, the right one is the one with the old MCL injury). So I started PT for the left knee this week.

So while pain contributed to the start of this round of "bad sleep", the causes of the pain have been treated and on a daily basis, I'm little to no pain right now.

I think some of us.....women especially......are very light sleepers. It dates back to us having to guard the cave at night, while the men were totally unconscious from catching that wooly mammoth.
Yep. Someone had to be awake to make sure the fire didn't die out in the wee hours of the middle of the night and someone had to tend to the babies and kids ....

That said, while I've never been as sound of a sleeper has hubby, I've also never been a super-light sleeper like some people around here are. Or perhaps more accurately: When my sleep is good, I'll wake up (usually post REM), be able to tell there's no need to be awake, and settle back down and get back to sleep all in about 5 minutes. And these post REM, 5 minute long wakes do NOT leave me exhausted in the morning so I don't worry about them at all. They are just part of my normal sleep patterns.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by robysue » Wed Mar 05, 2014 9:38 am

Pugsy wrote: Sometimes we just have to make compromises in an effort to get decent quality sleep and it's not like your AHI is in double digits when you do but even if it was over 5 all the time it would beat not getting any decent sleep due to the aerophagia and stuff. I am fortunate in that I haven't had many nights where aerophagia was an issue but I have had it on occasion so bad that I was physically ill the next day pretty much well into evening...so I understand. If I had to choose between maybe some less than stellar AHI reports and the aerophagia problem....the less than stellar AHI would win out.
Yep. The less than steller AHI is winning out for now. The troubling thing about the AHI is that it is slowly, but surely creeping upwards. And all three previous winters on PAP, the AHI went down during the winter only to go back up once spring allergies hit. And I don't think the trees are pollinating yet given the 6-8 inches of snow on the ground and the lows continuing to flirt with 0 much of the time ...

More seriously though. I tend to notice no difference at all between an AHI of 0.** and an AHI of 2.* in terms of how I feel the next day if the rest of the sleep is comparable. But once the AHI reaches 3.5, I start to feel some of the old "hand and foot pain" returning in the morning. And the absence of hand and foot pain is the primary reason I keep on paping. It's the one hands-down positive improvement in how I feel that I can clearly attribute to the PAP. And since Feb. 1, there have been 8 nights with an AHI > 3.0; 5 of those nights had an AHI > 3.5 and two of them had an AHI > 5.0. Hence the experiment with the pressures.
First and foremost we have to get to sleep and stay asleep as best we can. Your sleep is already so fragile that we simply don't have any extra room to have aerophagia mucking up things.
You are certainly right here. And what's even worse is that for me there's a bad feedback loop: Arousals leads to swallowing which leads to aerophagia which leads to more arousals which leads to more swallowing which leads to more aerophagia .....

The most interesting (if painful) lesson I think I learned two nights ago is that using the ramp in an effort to prevent the stomach from hurting while I'm awake and trying to get to sleep may increase the arousals that happen just as I'm dozing off ... In other words, with fixed pressure I'm damned if I do and damned if I don't in terms of using the ramp: Either way I get too much air in my stomach and that makes for a miserable night.

And I understand that the Ambien causes a bit of a fog in the AM. I get it too if I take Ambien and especially if I take it too late. I can't imagine the fog I would have if I took it as late as you do. And I cut my pills down to about a 1/3 of a 10 mg dose. I can't seem to get them down any smaller. I don't take it every night though. It's saved for special occasions.
At one point I was attempting to cut 10mg tabs in fourths. Not much fun. A quick call to the sleep doc get the script changed to 5mg tabs that I only have to cut in half. Much, much easier.

As for the lateness of the dose: My whole sleep phase is delayed. My targeted time in bed window is 1:00 AM to 8:30 AM, but I seldom make that 1:00AM bedtime due to not being sleepy yet. When I take an Ambien between 1:00 and 3:00, I' won't be getting out of bed before 8:30 or 9:00 anyway. So wake up is a full 6 to 7.5 hours after I take the Ambien ...
The mind can be a wonderful thing except when we want to shut it off so we can sleep...
Yep. My sleep doc has told me there's actually a new sleep med out there that works by turning off the WAKE channel in the brain rather than just sedating you. It's not yet won FDA approval, but he'd really like to put me on it once it does become available.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by avi123 » Wed Mar 05, 2014 2:04 pm

robysue wrote:
Pugsy wrote:
First and foremost we have to get to sleep and stay asleep as best we can. Your sleep is already so fragile that we simply don't have any extra room to have aerophagia mucking up things.
You are certainly right here. And what's even worse is that for me there's a bad feedback loop: Arousals leads to swallowing which leads to aerophagia which leads to more arousals which leads to more swallowing which leads to more aerophagia .....

The most interesting (if painful) lesson I think I learned two nights ago is that using the ramp in an effort to prevent the stomach from hurting while I'm awake and trying to get to sleep may increase the arousals that happen just as I'm dozing off ... In other words, with fixed pressure I'm damned if I do and damned if I don't in terms of using the ramp: Either way I get too much air in my stomach and that makes for a miserable night.
Question,

Is it possible that the way you use your nasal pillows mask and closing your mouth causes your extreme AEROPHAGIA because of METEORISM?

Check this from NEJM, dated Sep. 1972:

Meteorism Produced by Nasotracheal Intubation and Ventilatory Assistance


"INITIALLY perplexed by massive intestinal distention complicating the postoperative course of several of our patients on intermittent positive-pressure respiration and leading to rupture of the Stomach in one, we now think that ventilatory assistance through a cuffed nasotracheal airway was at fault. Use of the more comfortable and less injurious nasotracheal tube to replace an orotracheal tube has become commonplace when patients require postoperative ventilatory help for more than a day or two, but this substitution is not without hazard."

An excerpt:

"Since the problem has been observed mainly with a nasotracheal tube, rarely with a tracheostomy tube, but never in our experience with an orotracheal tube, we suggest that the ability of the patient to close his mouth is the essential element. When any cuffed intratracheal tube is used, the cuff is usually inflated just enough to permit a small air leak around it during the positive phase of ventilation, to diminish the likelihood of pressure necrosis of the cuff against the trachea.1 With an orotracheal tube, this leak is easily vented through the open mouth, but since the nasotracheal tube blocks one nostril and may also compress the other, air may be forced into the esophagus whenever the mouth is closed. Furthermore, with an orotracheal tube in place the patient has difficulty swallowing because he cannot fully close his mouth. A nasotracheal tube not only permits swallowing; it may stimulate the swallowing reflex. Analysis of the composition of gastric air may discriminate between these two potential causes."


Trying to explain it: if the air supply from the CPAP is thru your nostrils (air tight, with no leaks) and your mouth is also closed tight, there is no way for the air to leak out into the atmosphere during the CPAP inspiration stage. The intentional leak holes in the mask (if you use a full face mask) are not enough to vent the air. So the air is forced into your stomach. "A bite-block to prevent closure of the mouth may be helpful." So for us to prevent Aerophagia means to give in and create more intentional leaks even if it is affecting the accuracy of the XPAP treatment.

Description of one of the cases posted at NEJM:

"Case 3. An uneventful splenectomy was performed for relief of refractory hemolytic anemia in a 77-year-old woman with pulmonary insufficiency. The stomach was seen to be collapsed at the end of the operation, and the patient was soon alert, but several hours after a nasotracheal tube was inserted and ventilatory assistance was begun, she went into shock, vomited bloody material, and had gastric dilatation, which was then relieved by aspiration. Despite her lying quite still as a consequence of what proved to be myocardial and cerebral infarctions, the gastric distention progressed to such an extent that a sump catheter was necessary to keep the stomach empty. Neither at the re-exploration of the abdomen nor at post-mortem examination several weeks later was a cause for the distention disclosed."

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Last edited by avi123 on Wed Mar 05, 2014 2:24 pm, edited 5 times in total.
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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by avi123 » Wed Mar 05, 2014 2:05 pm

double post

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Last edited by avi123 on Wed Mar 05, 2014 3:34 pm, edited 1 time in total.
see my recent set-up and Statistics:
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http://i.imgur.com/3oia0EY.png
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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by avi123 » Wed Mar 05, 2014 3:29 pm

So, RobySue, you either go for low AHIs by eliminating leaks (in your case it's probably the mouth leak) and because of it suffer from extreme Aerophagia ("since the abdominal distention develops rapidly and is potentially lethal, it should be treated promptly with nasogastric suction"), or allow intentional mouth leak, and thus avoid the Aerophagia, but pay for it with higher AHIs.

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Last edited by avi123 on Wed Mar 05, 2014 3:37 pm, edited 1 time in total.
see my recent set-up and Statistics:
http://i.imgur.com/TewT8G9.png
see my recent ResScan treatment results:
http://i.imgur.com/3oia0EY.png
http://i.imgur.com/QEjvlVY.png

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by robysue » Thu Mar 06, 2014 1:14 am

avi123 wrote:Question,

Is it possible that the way you use your nasal pillows mask and closing your mouth causes your extreme AEROPHAGIA because of METEORISM?

Check this from NEJM, dated Sep. 1972:

Meteorism Produced by Nasotracheal Intubation and Ventilatory Assistance


"INITIALLY perplexed by massive intestinal distention complicating the postoperative course of several of our patients on intermittent positive-pressure respiration and leading to rupture of the Stomach in one, we now think that ventilatory assistance through a cuffed nasotracheal airway was at fault. Use of the more comfortable and less injurious nasotracheal tube to replace an orotracheal tube has become commonplace when patients require postoperative ventilatory help for more than a day or two, but this substitution is not without hazard."

An excerpt:

"Since the problem has been observed mainly with a nasotracheal tube, rarely with a tracheostomy tube, but never in our experience with an orotracheal tube, we suggest that the ability of the patient to close his mouth is the essential element. When any cuffed intratracheal tube is used, the cuff is usually inflated just enough to permit a small air leak around it during the positive phase of ventilation, to diminish the likelihood of pressure necrosis of the cuff against the trachea.1 With an orotracheal tube, this leak is easily vented through the open mouth, but since the nasotracheal tube blocks one nostril and may also compress the other, air may be forced into the esophagus whenever the mouth is closed. Furthermore, with an orotracheal tube in place the patient has difficulty swallowing because he cannot fully close his mouth. A nasotracheal tube not only permits swallowing; it may stimulate the swallowing reflex. Analysis of the composition of gastric air may discriminate between these two potential causes."
My understanding is that this is talking about invasive ventilation since they are talking about tubes down the trachea. That's not to say it's completely irrelevant, but having a tube put down your airway through either your nose or throat is not the same thing as using a nasal pillows mask that leaves the mouth completely uncovered.
Trying to explain it: if the air supply from the CPAP is thru your nostrils (air tight, with no leaks) and your mouth is also closed tight, there is no way for the air to leak out into the atmosphere during the CPAP inspiration stage. The intentional leak holes in the mask (if you use a full face mask) are not enough to vent the air. So the air is forced into your stomach. "A bite-block to prevent closure of the mouth may be helpful." So for us to prevent Aerophagia means to give in and create more intentional leaks even if it is affecting the accuracy of the XPAP treatment.
I use a nasal pillows mask, not a full face mask. And I do NOT use a chinstrap or tape or any other thing to keep my mouth closed. I don't make any efforts at all to keep my mouth closed. But I am normally a nose breather and always have been. And so unlike so many PAPers, my mouth doesn't just "open wide up" when I go to sleep.

That said: If I have congestion, I'll do a bit of mouth breathing now and then---not enough for me to worry about, but it's there. When I have a head cold or my seasonal allergies are really bad, I'll even do enough mouth breathing to trigger dry mouth problems. I'm also a world class drooler, even with my nasal mask on and that sometimes also causes a small uptick in my total leaks. I'll also sometimes wake up to annoying leaks right around the edges of the pillows as well. And as for my aerophagia? It's as bad (or worse) on a night where I'm doing significant amounts of mouth breathing because the congestion tends to wake me up, and excess arousals seems to be what triggers the swallowing of the excess air that leads to the aerophagia in the first place.
Description of one of the cases posted at NEJM:

"Case 3. An uneventful splenectomy was performed for relief of refractory hemolytic anemia in a 77-year-old woman with pulmonary insufficiency. The stomach was seen to be collapsed at the end of the operation, and the patient was soon alert, but several hours after a nasotracheal tube was inserted and ventilatory assistance was begun, she went into shock, vomited bloody material, and had gastric dilatation, which was then relieved by aspiration. Despite her lying quite still as a consequence of what proved to be myocardial and cerebral infarctions, the gastric distention progressed to such an extent that a sump catheter was necessary to keep the stomach empty. Neither at the re-exploration of the abdomen nor at post-mortem examination several weeks later was a cause for the distention disclosed."
Again, this was the result of invasive ventilation, which is a different can of worms than simple PAP therapy at extremely low pressures.

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Re: Fractured sleep, Ambien, dial wingin' and other things

Post by SleepWellCPAP » Thu Mar 06, 2014 9:10 am

Hi Robysue,

Clearly you are an expert in many elements addressed in this post, so I am just going to throw this out there in case it hasn't already been mentioned.

Rather than medications or equipment related issues, could your problem be related to sleep timing?

I have worked with a lot a shift workers over the years and they have been consistently the most difficult group to help attain a recupertive night's rest.

Do you think turning in a little earlier and on a consistent time schedule would be of any help? From what I have read melatonin production in the human body naturally starts to rise around 9 pm.
Jim Swearingen
Author of the book Sleep Well & Feel Great with CPAP, a definitive guide
For a free copy inquire with your local county librarian
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