CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

[-SWS]

even if you all (magically) manage to agree on one thing.

I love when people present highly-improbable hypotheticals.

SleepingUgly, I sure hope you do not shut up. This response was funny IMHO but probably true:

Oh, wait, if it's associated with GIFTEDNESS, then I scored very high on that hypersensitivity scale. I thought it was a measure of neuroticism, so I didn't endorse any items.

Oh, got to go, the rooster just crowed.

What do crows do?

According to the many kind people who provide me with directions while lost on vacations, they provide straight-line distances.

you might even say "There's an 'app' for that!":

I'm not EVEN mentioning the strange things I've absentmindedly placed in the fridge over the years.

Time is not such a big deal as most of us tend to practice subsistence farming so daily routines and the coming and going of the sun tend to mostly satisfy our temporal needs.

So cool.

[echo]

even if you all (magically) manage to agree on one thing.

I love when people present highly-improbable hypotheticals. .

What can I say? We all need a good laugh now and then

you might even say "There's an 'app' for that!":

I'm not EVEN mentioning the strange things I've absentmindedly placed in the fridge over the years.

Or WORSE, when you place something that SHOULD have gone in the fridge, somewhere ELSE. Have you not read Umberto Eco's "How to Travel with a Salmon and other essays"? (oh and 3 guesses why i love that author )

By the way, it looked like that phone was sitting on a barbecue grill . Makes sense, sticking it in the microwave would cause the phone AND the microwave to explode!

Back to topic, that hypersensitivity issue keeps coming back again and again. I wish they did some studies on that. Is there no way to measure hyper-sensitivity in the brain, maybe via functional MRI or SPECT/PET? They have shown for example that some people's pain perception is related to hypersensitivity in the brain (as in phantom limb syndrome) rather than in the nerves.... would be interesting to look at hypersensitivity & arousals during sleep.

[blizzardboy]

What do crows do?

Muffy

They play footy - carn the Crows.

http://www.afc.com.au/

[blizzardboy]

... would be interesting to look at hypersensitivity & arousals during sleep.

I'm itching for this. Put me first in the queue. Pity they don't dispense MRI scans like they do Prozac.

[unadog]

Oh, got to go, the rooster just crowed.

What do crows do?

Muffy

Roost

[blizzardboy]

if blizzardboy's EF is <40%, we can certainly take this discussion in a whole new direction.

Muffy

What tests are required to quantify the performance of my heart? Ultrasound of valve?

[Muffy]

An echocardiogram, but before you go down that road, what kind of sports do you do, and with what intensity? Have you ever had a pulmonary function test?

I think you should get and review all your data first before you go too much further. For example, you're saying you have a "bunch of centrals", but if a "bunch" is 20, and they're all isolated and post-arousal, you may not be getting that much bang for the buck with an ASV.

Muffy

[blizzardboy]

An echocardiogram, but before you go down that road, what kind of sports do you do, and with what intensity? Have you ever had a pulmonary function test?

I think you should get and review all your data first before you go too much further. For example, you're saying you have a "bunch of centrals", but if a "bunch" is 20, and they're all isolated and post-arousal, you may not be getting that much bang for the buck with an ASV.

Muffy

I ceased regular sport since my children arrived. I used to play cricket. Before that I played footy (Australian Rules).

I can't recall having had my pulmonary function tested.

When my free website gets up and running I'll post my sleep reports. Thanks for your input Muffy.

[blizzardboy]

If you happen to score borderline or high on this non-scientific HSP screening questionnaire then I personally suspect that your stimulus/response equation to poor sleep and EDS is probably highly multifactorial as a matter of both hypersensitivity and hyper-responsiveness.

FWIW I scored 21/25 - bit touchy, eh?

[Muffy]

Before that I played footy (Australian Rules).

I had you pegged for a "footballer"!

I ceased regular sport since my children arrived.

That's a drag. If you were able to continue running around the field doing sprints for an hour, and that ability had not changed, that would have been a great test to rule out underlying cardiac, pulmonary and neurological problems.

Looking forward to seeing the data.

Muffy

[Muffy]

Prozac suppresses REM.

It also generates SSRI Withdrawal Syndrome when you suddenly stop it, which should basically TFU the sleep architecture.

Muffy

[blizzardboy]

Looking forward to seeing the data.
Muffy

Here 'tis (only 10 downloads possible on this temporary link)

http://rapidshare.com/files/375745606/P ... d.pdf.html

There is a problem with my free webpage that will hopefully get sorted out tomorrow.

[Muffy]

OK, so right off the bat you can get rid of hypoventilation, hypercapnia, bradycardia, and vagal events.

Your sleep architecture would more likely be rated as poor. Fluoxetine effect appears to persist (it has a long half-life). SSRI discontinuation is unclear as an additional confounder.

I think the next part of plan needs to consider improvement of sleep architecture via addressing sleep hygiene and sleep consolidation and deciding how/if you want to address those PLMs.

Muffy

[-SWS]

Looking forward to seeing the data.
Muffy

Here 'tis (only 10 downloads possible on this temporary link)

Well, I wasn't one of the lucky 10 to download the files. However, I'm surprised to hear that all these---some of which are known to present with highly transient characteristics from week-to-week---can be so readily dismissed with the data provided in that download link:

OK, so right off the bat you can get rid of hypoventilation, hypercapnia, bradycardia, and vagal events.

_____________________________________________________________________________________________________________________________

On Edit: I just downloaded the file successfully. Not sure what went wrong the first time. I saw this erroneous average heart rate followed by the :

Average heart rate during sleep: 20
Number of Bradycardic periods: 0

I certainly wouldn't put hypoventilation, hypercapnia, bradycardia, or vagal events on the front burner or back burner based on that data. However, if I episodically returned wild swings in my home-measured BP, SpO2, or ASV data, then I'd take a close look at some of those possibilities. My understanding is that some cardiac and central symptoms can be highly transient---especially during onset of certain diseases.

[blizzardboy]

OK, so right off the bat you can get rid of hypoventilation, hypercapnia, bradycardia, and vagal events.

Your sleep architecture would more likely be rated as poor. Fluoxetine effect appears to persist (it has a long half-life). SSRI discontinuation is unclear as an additional confounder.

I think the next part of plan needs to consider improvement of sleep architecture via addressing sleep hygiene and sleep consolidation and deciding how/if you want to address those PLMs.

Muffy

Thanks for that Muffy. Maybe it was an error in judgement to stop taking fluoxetine prior to the study, I'm not sure. I wanted to know my sleep results without fluoxetine in my system - a drug-free baseline of sorts.

Remember that I had the home sleep study last October which reported an moderate OSA (AHI=36) with "bunches of centrals" and I didn't cease fluoxetine for that one.

Given that I apparently have a lot of PLMs I certainly would be interested to know what are the options for treatment.

Probably good just to give my body a good run on the ASV first. What do you reckon?