azdj wrote:Snoredog: I find it interesting that you seem to have a pretty complex sleep issue, including centrals, yet find that one of the least expensive machines , Goodnight 420 E, seems to work best for you. I have been looking at getting a second machine for travel for my BIPAP ST, but have hesitated because of the $5,000 cost of the auto bipaps with ST. Do you find that with your machine that your CO2 is regulated to where you don't need the ST? Just curious - I find your theory extremely interesting and am exploring how it might apply to others with centrals - the ST is working OK but I don't think it is giving me the best results and my centrals continue to be high, forcing the machine initiated breaths to be high. It is all inter-related somehow and that all seems too complicated for my sleep doctor (or his nurse who is the "gate-keeper"). Right now I am leaning towards trying the Bipap Auto SV or Bipap AVAPS, but don't want to pay $5K out of pocket unless pretty sure it is the right thing for somebody with limited obstructive events, but higher hyponia and centrals.
If I go by the results of my 4 PSG's, I have to conclude I have a form of CSDB, I have an intolerance to CPAP with CA's and Mixed apnea, but I conclude a very mild form of it. I am post stroke one of the characteristics found with CDSB, but I don't really believe the stroke played any part of my SDB, I think it is quite the opposite, SDB contributing to the year of TIA's and finally 2 strokes. My O2 levels during my first PSG were in the 65% range. My AHI wasn't all that bad at 72 per hour, in addition to that I had spontaneous noted at 29 per hour.
I've tried CPAP, never could find a set pressure that would work for any amount of time. Problem with that was I was awakening 3 or more times per night, many times in a full sweat and panic. That was a Remstar Pro, then a 420S, I then tried autopaps starting with a 420e probably the first one cpap.com ever shipped, it died on me and started operating erratically after 3 days use. I sent it back where I exchanged it for a Remstar Auto tank (non-Cflex) at my request. Next, I bought a Resmed Spirit S7, that was also pretty much a disaster for me. All it would do was run up in pressure as soon as I turned it on. I sold that one to kteague (sorry Kathy ). Later I updated the Remstar Autos to newer versions as new firmware came out. Went from non-Cflex to Cflex to Aflex. My BIL also has OSA and we'd swap machines around to try different machines. Think I owned 3 or 4 versions of the tank version of the Remstar Auto including a M series (actually 2 M series, one Cflex Auto and finally Aflex). Cflex wasn't so bad but Aflex simply doesn't agree with my SDB condition, similar result as seen in the lab with bilevel sleep became a train wreck (shameless plug: have the Aflex For Sale complete setup, w/humidifier extra tanks, including EncorePro 1.8.49 and reader, PM me if interested).
I have also been titrated on Bipap during my last PSG, didn't do so well with it, don't know if it was lack of experience by the tech or what but they tried bilevel and went back to cpap as sleep came apart. But I don't think they even knew about CSDB during that last PSG as I haven't been back to see my sleep specialist in over 6 years and don't intend to return any time soon.
Why I selected the 420e. Note: Current 420e is my 2nd 420e and 3rd if you want to count my 420s I owned in the past. It was only after trying everything else and understanding how they functioned did I return back to the 420e. My theory is with CSDB you want to treat the obstructive events seen and avoid any response to CA seen. More difficult thing to do with mixed apnea, but doable in my case.
I found the 420e has the settings and technology I need to treat me the best. You can control and limit how it responds to Flow Limitation, you can control how it responds to Apnea and control how it responds to obstructive apnea over 10 cm and/or if CA's are a problem limit apnea response below that threshold. No other machine on the market other than the new Sandman Auto can you tweak those parameters which is what allowed that machine to work for me.
CA is not my primary disorder, I don't have any waxing or waning commonly found with CSR nor do I think it would remotely work in that case. If your disorder is primarily CA or CSDB you need a machine that can manipulate and stablize your breathing in order to eliminate the CA. With the 420e and how I have it set up, it effectively treats my OSA while leaving the CA's alone. I keep my Minimum pressure low, limit how it can respond to apnea and flow limitations and use a mask I know retains more CO2. I know from years of use and observing reports, my apnea threshold is 9, if I go over that at the wrong time I'll have all kinds of CA's. With the Silverlining reports I can see my results. I lowered Command on Apnea from 10 cm to 9.0 cm, disabled IFL1 which is command on Flow Limitation and it pretty much keeps CA's to non-existent or only 1 or 2 per night, I can live with that.
So will it work for you as backup? I cannot say without looking at your daily reports and knowing your SDB condition. You have to know what your current machine is doing, with a ST it will switch from Spontaneous mode to Timed backup mode in the presence of CA. 420e doesn't do anything of the sort it simply does a better job at differentiating the difference between obstructive and central events. For the latter it doesn't do anything where your ST might switch to Timed backup mode if it senses you have stopped breathing. If your machine is switching several times per night it may not work for you, it may if you spend majority of time in Spontaneous mode and don't have a loss to spontaneous respiratory drive. If you have any AHI info from your current machine that would be helpful, just understand there is no mode switching should you stop breathing as with your current machine, but I don't know how you have that set up as it can be in CPAP, BIPAP, S or S/T mode. If it is being run in S mode then you don't have any timed backup to revert to even if it is set up.
But if I was to choose any other non-ST machine for emergency use it would be the 420e or the new Sandman Auto, in fact I'd lean towards the Sandman, they surely have made improvements to it over the 420e. From seeing the reports I'd have to say they have only improved upon it while I still prefer the 420e's form factor.
My pressure is low usually under 10 cm, my titrated pressure was 9 cm 8 years ago still is today. But there are times the 420e reports going up as high as 14 cm to take care of hypopnea or chase a snore but not often.
someday science will catch up to what I'm saying...