0.0

General Discussion on any topic relating to CPAP and/or Sleep Apnea.
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Papit
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Re: 0.0

Post by Papit » Sun Jun 30, 2013 3:59 pm

DreamDiver wrote:
avi123 wrote:... Resmed would not let CAs to show, untreated, from a machine that was designed to eliminate them. To check the reliability of those Resmed VPAP Adapt ASV machines you need a third party to do it. Something like the Consumer Reports but for CPAP users.
Technically, we should be able to do it by looking carefully at the graphs. CA's are fairly easy to spot in a 10-minute window or 5-minute window, confirmable in a minute/thirty-second window.
Gents, while ResMed does not distinguish between OA and CA in the Adapt reports and graphs (it combines them), it certainly DOES show and report them. I did my own test. A few minutes before turning off my machine on 6/27, I held my breath three times that I guesstimated were for 15, 25, and 35 seconds. See charts below. Notice how promptly the machine elevates its pressure to push air into me and treat for the three (intentional) halts in my air flow. (Re. the ongoing discussion about the quirky appearance of a Flow Limitation graph for an Adapt machine, notice that no flow limitations appear on the graph in sync with my three extended halts in breath.)

Image

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Re: 0.0

Post by DreamDiver » Sun Jun 30, 2013 4:29 pm

Papit wrote:... A few minutes before turning off my machine on 6/27, I held my breath three times that I guesstimated were for 15, 25, and 35 seconds. ...
Did you hold your breath with your throat closed or with your throat open? Could you zoom in at a five minute window on just the shorter of the two example apneas giving the flow graph just below the event graph?

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Re: 0.0

Post by Papit » Sun Jun 30, 2013 6:54 pm

DreamDiver wrote:
Papit wrote:... A few minutes before turning off my machine on 6/27, I held my breath three times that I guesstimated were for 15, 25, and 35 seconds. ...
Did you hold your breath with your throat closed or with your throat open? Could you zoom in at a five minute window on just the shorter of the two example apneas giving the flow graph just below the event graph?
Thanks for your interest, DreamDiver. Sure, here's the zoomed in 5-minute view of the three hold-breath (over 10 seconds) tests I did with Flow Rate graph just below it. No, my tongue was not back blocking my throat shut. As can be seen here, no attempt is made by ResMed to hide these apneas, which I think would probably be graphed as Centrals IF centrals were graphically distinguished from Obstructives in Adapt graphs.

Image

Note that I had to use SH to see the Flow Rate graph. Although I see "Flow" (in addition to "Flow Limitation" and the usual graphs) listed under Tools>Options>Preferences>Detailed Graphs>Graphs, no "Flow" graph comes up for me except "Flow Limitation". Curious, but possibly explainable by the unit's more recent manufacture as I received it only two weeks ago. Maybe they tweaked something. Anybody have a tech support number for the company?

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Last edited by Papit on Sun Jun 30, 2013 7:36 pm, edited 1 time in total.
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Re: 0.0

Post by avi123 » Sun Jun 30, 2013 7:10 pm

Are we going to deal now with Papit's Flow Limitation?



Image

Image

Image


Check this about Flow Limitation (consisting of RERAs and UARs):

A source for a link:

http://www.apneaboard.com/forums/Thread ... e-Syndrome

Do you have Upper Airway Resistance Syndrome (UARS)?

Clinical Features

Patients with UARS have symptoms similar to those seen in OSAS, although there are some distinct features. Much of the research performed has attempted to identify and describe a group of patients with significant daytime sleepiness and disrupted sleep, but without the other dominant clinical features seen in OSAS. Typical symptoms reported by patients with UARS include excessive daytime sleepiness, fatigue, difficulty concentrating, morning headaches, and unrefreshing sleep. There can be also be a significant impairment in daytime functioning; a recent study demonstrated that subjects with UARS performed worse than patients with obstructive sleep apnea hypopnea syndrome and normal control individuals on different aspects of the Psychomotor Vigilance Task. In a separate study, upwards of 30% of subjects with UARS had abnormal sleep-onset latency on the Maintenance of Wakefulness Test. Individuals with abnormal airway anatomy are at increased risk, including those with a decreased retrolingual space, narrow nasal passages, or a small neck circumference. Patients are typically not obese, with a mean BMI often <25 kg/m. They are also usually younger than those in whom OSAS is diagnosed, with a mean age of approximately 38 years. Snoring is not a requisite symptom, with 10% to 15% or more of patients having never or only intermittently snored.

Patients with UARS are also more likely to report symptoms of frequent nocturnal awakening with difficulty falling back to sleep. This is thought to be a potential reason for increased complaints of insomnia amongst patients with UARS, including sleep onset and sleep maintenance problems. In addition to difficulties with acute insomnia, patients with UARS also have an increased likelihood of carrying a diagnosis of chronic insomnia. Other notable complaints include parasomnias, especially sleepwalking, sleep talking, and sleep terrors. Patients may also have symptoms of abnormal autonomic function, including lightheadedness or dizziness on rising from a supine or sitting position, cold hands and feet, and low resting blood pressures (defined as a systolic BP <105 mm Hg with a diastolic BP <65 mm Hg). In a study of 400 patients with UARS, more than 20% met criteria for low BP, a significantly higher prevalence when compared with people who have OSAS (0.6%) or insomnia (0.9%). Interestingly, all subjects in the study had evidence of a small oral cavity on examination with a narrowed airway space dimension on cephalometric radiographs, consistent with other reports. Lastly, patients with UARS have increased rates of symptoms such as gastroesophageal reflux, muscular pain, diarrhea, abdominal pain, depression, and anxiety. This has led some authors to suggest a link between UARS and functional somatic syndromes, such as irritable bowel syndrome, chronic fatigue syndrome, and fibromyalgia. In a study of 75 subjects equally divided into three groups (UARS, mild to moderate OSAS, and severe OSAS), those with UARS were more likely to report symptoms of headache, irritable bowel symptoms, and sleep-initiation insomnia. Subjects with UARS were also more likely to have alpha intrusion during slow-wave sleep, a polysomnographic finding described in a number of fatigue syndromes. In children with UARS, symptoms consistent with attention deficit disorder or attention deficit hyperactivity disorder may be present, with behavioral changes leading to poor school performance.


________________________________________
Clinical Features Associated With UARS

Daytime symptoms:

Excessive daytime sleepiness
Fatigue
Morning headaches
Myalgia’s [muscle pain]
Difficulty concentrating


Sleep disturbances:

Frequent nocturnal awakenings
Difficulties initiating sleep
Insomnia
Bruxism [teeth clenching]
Restless leg syndrome
Unrefreshing sleep

Autonomic nervous system:

Hypotension
Orthostasis [maintenance of an upright standing posture]
Cold hands and feet

Functional somatic syndrome associations:

Depression
Anxiety
Chronic fatigue syndrome
Irritable bowel syndrome
Fibromyalgia

Polysomnographic abnormalities Increased RERAs:

Increased nocturnal arousals
Increased CAP rate [cyclical alternating pattern in EEG]
Alpha intrusion during sleep

Treatment

The optimal treatment for patients with UARS is not currently known. Continuous positive airway pressure (CPAP) has been quite useful in the treatment of sleep-disordered breathing and there are some notable positive results in CPAP treatment of UARS. In a study of 15 heavy snorers with clinical evidence of UARS, treatment with nasal CPAP was associated with decreases in observed nocturnal arousals on polysomnography and decreases in mean sleep latency times on multiple sleep latency testing (MSLT) after several nights of treatment. A follow-up study of 15 subjects (in the original description of UARS) with daytime sleepiness and fatigue and who had undergone a therapeutic trial of positive pressure therapy reported similar findings. After treatment with approximately a month of nasal CPAP, significant improvements were seen in mean sleep latency times on MSLT (5.3 minutes vs 13.5 minutes), Pes nadir pressure (–33.1 cm H2O vs –5.3 cm H2O), amount of slow-wave sleep (1.2% vs 9.7%), and EEG arousals (31.3 vs 7.9 events/hour of sleep). Along with an improvement in sleep latency times on MSLT, there were subjective reports of improved daytime symptoms. Lastly, in a study of 130 postmenopausal women with chronic insomnia and evidence of UARS (n=62) or normal breathing (n=68), treatment with either nasal turbinectomy or nasal CPAP was associated with improvements in subjective reports of sleep quality as measured with a visual analog scale as well as mean sleep latency times on polysomnography.19 Despite the growing body of evidence supporting the use of positive pressure therapy for UARS patients, it remains difficult to obtain therapy. In a follow-up study of more than 90 patients conducted 4 to 5 years after the initial diagnosis of UARS was made, none of the subjects were receiving CPAP treatment; the main rationale given was that their insurance provider declined to provide the necessary equipment.1 Formal follow-up clinical evaluations of these patients noted significant worsening in their sleep-related complaints, with increased reports of fatigue, insomnia, and depressive mood. More disturbingly, prescriptions for hypnotics, stimulants, and antidepressants increased more than fivefold.

Other interventions, such as surgery or oral appliances, have also been used with some success in the treatment of patients with UARS. Procedures such as uvulopalatopharyngoplasty, laser-assisted uvuloplasty (LAUP), septoplasty with turbinate reduction, genioglossus advancement, and radiofrequency ablation of the palate have all been described in the literature.37-40 A study of LAUP in nine patients with UARS who underwent uvulopalatopharyngoplasty (n=2), multilevel pharyngeal surgery (n=1), or LAUP (n=6) reported improvements in subjective daytime sleepiness as measured with Epworth Sleepiness Scale scores.37 In the two patients for whom postoperative polysomnographic data was available, significant improvements in Pes nadir pressures were seen. But patients had several interventions and it is difficult to assess which one was successful. A study of 14 patients with UARS who underwent radiofrequency ablation of the palate also reported improvement in subjective sleepiness, with concurrent improvements in Pes nadir levels and reports of snoring.40 However, prior reviews of the available literature have noted that many of the studies evaluated small numbers of patients, consisted of uncontrolled case reports or series without clear characterization of the subjects enrolled, and had no consistent end points for an adequate evaluation of efficacy.39 Further investigation is required to determine the specific role for surgical intervention in these patients. Other authors have also reported successful treatment of UARS with use of oral appliances, although these studies suffer from the same limitations as the surgical literature.41 In children, orthodontic approaches, such as maxillary distraction or use of expanders, have also shown promising results.

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Last edited by avi123 on Mon Jul 01, 2013 10:01 am, edited 3 times in total.

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DreamDiver
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Re: 0.0

Post by DreamDiver » Sun Jun 30, 2013 7:27 pm

Papit wrote:... Note that I had to use SH to see the Flow Rate graph. Although I see "Flow" (in addition to "Flow Limitation" and the usual graphs) listed under Tools>Options>Preferences>Detailed Graphs>Graphs, no "Flow" graph comes up for me except "Flow Limitation". Curious.
Curious indeed. Fantastic! Thanks. I'm learning a lot. I'd never have guessed that ResMed would hide flow on the ASV, and I'm not sure why they would. There is probably a file edit for that to make it show on ResScan, if you want to. I'm guessing one of the other forum members will figure it out before I do, if it hasn't been figured out already, but since the data exist, it should not be too difficult to make ResScan see your flow data on the ASV.

I don't know enough to make suggestions about pressure changes, but I'm interested in following along on to hear how things progress. Again, thanks.

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Re: 0.0

Post by NateS » Sun Jun 30, 2013 7:46 pm

DreamDiver wrote:
Papit wrote:... Note that I had to use SH to see the Flow Rate graph. Although I see "Flow" (in addition to "Flow Limitation" and the usual graphs) listed under Tools>Options>Preferences>Detailed Graphs>Graphs, no "Flow" graph comes up for me except "Flow Limitation". Curious.
Curious indeed. Fantastic! Thanks. I'm learning a lot. I'd never have guessed that ResMed would hide flow on the ASV, and I'm not sure why they would. There is probably a file edit for that to make it show on ResScan, if you want to. I'm guessing one of the other forum members will figure it out before I do, if it hasn't been figured out already, but since the data exist, it should be too difficult to make ResScan see your flow data on the ASV.

I don't know enough to make suggestions about pressure changes, but I'm interested in following along on to hear how things progress. Again, thanks.
Would these be relevant or helpful?:
idamtnboy wrote: 10/26/2011
OK, I just happened to remember. You have to make some edits to the resscan.xml file in order to get Resscan to display it. Search flow limitation and xml. You should be able to find the thread where it's discussed.
viewtopic.php?f=1&t=70181&p=649833&hili ... ml#p649833

and:
Editing the ResScan XML Files to Show Me What I want
viewtopic.php?f=1&t=64986&p=606916&hili ... ml#p606916

Regards, Nate

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Re: 0.0

Post by DreamDiver » Sun Jun 30, 2013 7:50 pm

NateS wrote:Would these be relevant or helpful?:
...
viewtopic.php?f=1&t=70181&p=649833&hili ... ml#p649833

and:
Editing the ResScan XML Files to Show Me What I want
viewtopic.php?f=1&t=64986&p=606916&hili ... ml#p606916
...
Thanks Nate

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Re: 0.0

Post by Papit » Mon Jul 01, 2013 1:24 am

NateS wrote:
DreamDiver wrote:
Papit wrote:... Note that I had to use SH to see the Flow Rate graph. Although I see "Flow" (in addition to "Flow Limitation" and the usual graphs) listed under Tools>Options>Preferences>Detailed Graphs>Graphs, no "Flow" graph comes up for me except "Flow Limitation". Curious.
Curious indeed. Fantastic! Thanks. I'm learning a lot. I'd never have guessed that ResMed would hide flow on the ASV, and I'm not sure why they would. . . .
Would these be relevant or helpful?: (earlier links)
idamtnboy wrote: 10/26/2011
Regards, Nate
-Nate and DreamDiver, you put me on the right track with your comments and questions. I can now bring up both Flow and Flow Limitation in the Detailed Graphs. Check it out and see the way I did it below the image. I think all S9 VPAP Adapt users (maybe all S9 users) can do the same to view Flow and Flow Limitation and/or other graphs. ResMed isn't hiding the charts. It's more a matter of navigation and selecting what you want (and don't want) to see.
Image

Select a date within the last couple days; then go into the Report menu and create a report. Select Customize, then expand 'Detailed Graphs' in the right-hand column. Expand 'Detailed Graphs' again under Available Items on the left. Now select Flow Limitation and Flow from the left if you don't have and want to add either or both graphs and then 'Add' them to your current list of graphs. If you want to get rid of any current detailed graphs that you don't want (clutter), 'Remove' them from your list on the right. You can always go back when you want to reconfigure your list. This is also a good opportunity to resequence the order in which the graphs are displayed to you. When done, click OK and do a File>Save.
Best regards. Thanks again for working on this with me.

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Re: 0.0

Post by DreamDiver » Mon Jul 01, 2013 7:07 am

Papit wrote: -Nate and DreamDiver, you put me on the right track with your comments and questions. I can now bring up both Flow and Flow Limitation in the Detailed Graphs.
Me smacking my forehead. "!" I should have remembered the first thing to check is whether or not some graphs are simply omitted from the graphs section. Simple solution.

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Re: 0.0

Post by avi123 » Mon Jul 01, 2013 9:34 am

DreamDiver wrote:
Papit wrote: -Nate and DreamDiver, you put me on the right track with your comments and questions. I can now bring up both Flow and Flow Limitation in the Detailed Graphs.
Me smacking my forehead. "!" I should have remembered the first thing to check is whether or not some graphs are simply omitted from the graphs section. Simple solution.
Comment,

Is it possible that Papit was not familiar with your "ResScan Video Tutorial"?

ResScan Video Tutorial: http://tinyurl.com/8yf7g7q

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Re: 0.0

Post by JohnBFisher » Mon Jul 01, 2013 10:07 am

DreamDiver wrote:
JohnBFisher wrote:...
Well, that might be the Resmed Spokesman's definition of no central apnea, but if you have serious enough problems, a central apnea WILL occur. I offer my own example. This was from a PR System One ASV unit, which does not pretend that no central apnea occurs.

IMAGE
Sure, even when I stopped breathing there was some air movement because the unit quickly ramped up the air pressure. But the point is that my body was not responsible for that. I was in the middle of a series of central apneas.
JohnBFisher, I am unfamiliar with some of the stuff I'm seeing on the PR graph you provided. Excluding wave forms, which ticks/markings depict centrals? Also, am I right in seeing that you have large leak all the way through? Is the quattro fx comfortable on the nose bridge for you?
DreamDiver, this graph is the waveform graph from a Respironics ASV unit in Encore Basic. That particular graph does not show what is scored as an obstructive or central apnea. I use it only as an example of how much my ASV units must sometimes help me. And in this case, I refute the point from the Resmed Spokesman that with an ASV unit there will be no central apneas. Point is, the apneas can and will occur. But the machine will intervene (as mine did). But the apneas can still occur. It's a different definition. But I think it's an important difference. I think my definition is more realistic with less "sales speak".

Yes, you are correct that I was also struggling with a large leak. I ended up changing my mask cushion. But those apneas were not the result of the leak. In my case, I sometimes struggle with horrible sleep. It comes and goes .. but not on any pattern to which I can identify. But when it's bad, the apneas are more like that graph than not.

I find the Quattro FX mask quite comfortable. I use a mask liner, which helps the seal hold. And when it does not, it tends to not be as loud when it leaks.

Hope that helps.

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Re: 0.0

Post by StuUnderPressure » Mon Jul 01, 2013 10:08 am

DreamDiver wrote:
Papit wrote: -Nate and DreamDiver, you put me on the right track with your comments and questions. I can now bring up both Flow and Flow Limitation in the Detailed Graphs.
Me smacking my forehead. "!" I should have remembered the first thing to check is whether or not some graphs are simply omitted from the graphs section. Simple solution.
I can also see both the Flow & Flow Limitation in the Detailed Graphs in my plain vanilla S9 AutoSet.

As some have already said, all you have to do is choose to include them.

So, if you are not now seeing some graphs you hear others refer to, you may have to simply go in & "choose" to see those graphs.

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Re: 0.0

Post by JohnBFisher » Mon Jul 01, 2013 10:33 am

Papit wrote:Image
Papit, a couple comments.

First, it would not do any good to call the technical support folks and talk about a SleepyHead graph. Since SleepyHead is open source, it's not something with which Resmed would be able to help you. Further, even with ResScan, I doubt you would be able to get help at the detail with which you are examining your graphs.

Second, I think the "flow limitation" is an artifact of the algorithm used to identify possible limitation of flow and a precursor to snoring.

Rather than worry about the flow limitation graph, the pattern of the flow rate is more informative. In particular we see:

Image
Note the decrescendo that occurs over and over again. You start with a large breath and then the respiratory gradually decreases until to stop breathing. While the ASV unit is doing it's job, this pattern tends to repeat. It is NOT a Cheyne-Stokes Respiration. It appears more as if you respiratory drive just is not what it should be.

Now within that pattern we see some occasional "hiccups" in the flow rate. The software interprets those as flow limitations. I doubt seriously that's what they were. It just appears that respiratory drive was fizzling out a little early, but regained normal downward slope after those 'events'.

Image
Is there something you need to worry about? No. If you were not using an ASV unit, I would worry for you. But your ASV unit helps with the respiration even when you are not able to do so. As long as you are feeling fine, I would not worry too much. If you start to feel horrible, then you will probably need to discuss your situation with your sleep doctor.

Hope that helps.

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Re: 0.0

Post by DreamDiver » Mon Jul 01, 2013 11:35 am

JohnBFisher wrote:... DreamDiver, this graph is the waveform graph from a Respironics ASV unit in Encore Basic. That particular graph does not show what is scored as an obstructive or central apnea. I use it only as an example of how much my ASV units must sometimes help me. And in this case, I refute the point from the Resmed Spokesman that with an ASV unit there will be no central apneas. Point is, the apneas can and will occur. But the machine will intervene (as mine did). But the apneas can still occur. It's a different definition. But I think it's an important difference. I think my definition is more realistic with less "sales speak".
Okay, I misunderstood and thought you were saying PR actually does mark CA's, when in fact, like the ResMed equivalent, they've elected to not mark them. Like you, I believe it would be more useful if they would. At the very least they should include shaded area that shows when SV attempts to circumvent an upcoming apnea.
JohnBFisher wrote:Yes, you are correct that I was also struggling with a large leak. I ended up changing my mask cushion. But those apneas were not the result of the leak. In my case, I sometimes struggle with horrible sleep. It comes and goes .. but not on any pattern to which I can identify. But when it's bad, the apneas are more like that graph than not.
No doubt. If you find a pattern, I hope you'll share. It's been a while since I've used a PR machine and am trying to catch up my understanding. Thanks.
JohnBFisher wrote:I find the Quattro FX mask quite comfortable. I use a mask liner, which helps the seal hold. And when it does not, it tends to not be as loud when it leaks.
I've got a quattro that I've been using the last few nights because my go-to mask seems to be wearing out (large leakage for no visible reason). I have been thinking about trying the Quattro FX. Thanks.

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Re: 0.0

Post by JohnBFisher » Mon Jul 01, 2013 1:13 pm

DreamDiver wrote:
JohnBFisher wrote:... DreamDiver, this graph is the waveform graph from a Respironics ASV unit in Encore Basic. That particular graph does not show what is scored as an obstructive or central apnea. I use it only as an example of how much my ASV units must sometimes help me. And in this case, I refute the point from the Resmed Spokesman that with an ASV unit there will be no central apneas. Point is, the apneas can and will occur. But the machine will intervene (as mine did). But the apneas can still occur. It's a different definition. But I think it's an important difference. I think my definition is more realistic with less "sales speak".
Okay, I misunderstood and thought you were saying PR actually does mark CA's, when in fact, like the ResMed equivalent, they've elected to not mark them. Like you, I believe it would be more useful if they would. At the very least they should include shaded area that shows when SV attempts to circumvent an upcoming apnea. ...
No, no. Respironics with the Encore software (including Encore Basic) DOES identify central apneas. This particular graph does not. That's all.
DreamDiver wrote:
JohnBFisher wrote:Yes, you are correct that I was also struggling with a large leak. I ended up changing my mask cushion. But those apneas were not the result of the leak. In my case, I sometimes struggle with horrible sleep. It comes and goes .. but not on any pattern to which I can identify. But when it's bad, the apneas are more like that graph than not.
No doubt. If you find a pattern, I hope you'll share. It's been a while since I've used a PR machine and am trying to catch up my understanding. Thanks. ...
If I find a pattern, I'll be certain to let folks know. I'm starting to think I see one, so I'll try to remember to update everyone.
DreamDiver wrote:
JohnBFisher wrote:I find the Quattro FX mask quite comfortable. I use a mask liner, which helps the seal hold. And when it does not, it tends to not be as loud when it leaks.
I've got a quattro that I've been using the last few nights because my go-to mask seems to be wearing out (large leakage for no visible reason). I have been thinking about trying the Quattro FX. Thanks.
I like the FX much more than I do the Quattro. I had to use the Large FX mask, since my mouth tends to hang open during sleep. The Medium (default size) FX mask would end up in the middle of my mouth, instead of below my mouth. The large FX fits me better. So, you might want to be certain you can return the FX if you get the medium. .. Just an FYI for you.

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Mask: Quattro™ FX Full Face CPAP Mask with Headgear
Additional Comments: User of xPAP therapy for over 20 yrs. Resmed & Respironics ASV units with EEP=9cm-14cm H2O; PSmin=4cm H2O; PSmax=15cm H2O; Max=25cm H2O
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