Some time back I posted to a reflux(gerd) group the increasing awareness of a rebound effect of the PPI's that they may be causing more reflux than it is preventing.
One of my first discoveries on cpap was that my lifelong severe reflux magically disappeared.
The PPI makers may just have their own brand of crack cocaine. Get em'
hooked for life.
My wife was put on nexium by a pulmonologist because he thought the
cough and spasms may be due to subclinical reflux. She did not have
this nor had she ever had any degree of reflux. She rarely even used
tums etc.
About 4 years later- a couple of months ago, i suggested she get off
them since she was having no respiratory problems since we had to
euthanize our dog. Sounds like it was pet allergy all the time.
Being a Pharmacist, I am aware of rebound in such things as afrin and
visine etc. They can be a real problem to come off of.
Anyway, we got loaded up on tums and zantac as soon as she d/c the
NEXIUM, the reflux was rather severe, even though she had never had
reflux to start with. I told her to continue with increasing zantac
and tums and hope she could wait it out.
She really seems to be having withdrawals and I do not know when or if
there will be a time she will again not have reflux.
A big question for the osa community is for those who were on the PPI's BEFORE you were on PAP.
I suspect that many are still on them because of the rebound while those on zantac, tagamet etc have no further problem.
Is it possible the cure is worse than the problem?
do a google on rebound and nexium- ppi- prilosec etc and see what you
think.
Any suggestions? thoughts
Reflux/osa/ Purple pill rebound
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Guest
Wonderful post TomJax, My husband had GERD for many years before he was diagnosed with OSA and began cpap therapy, which resolved the years of nighttime reflux. For many years he had used liquid antacids at bedtime and woke to use them during the night. Before Nexium came out, when Prilosec was the current medical miracle, and not yet OTC, our family doctor prescribed it for reflux. Of course, due to the apnea, he continued to have night episodes with reflux. My understanding is that as the diphram works harder to expand, and draw air into a closed airway, the vacuum sucks the stomach contents up, and into the airway.
When he reported continued reflux to the Dr. he referred him to an internist and suggested he increase his Prilosec. The next day, the internest suggested he increase his Prilosec.
Now having tripled his prilosec intake, he began having abdominal pain and vomiting, with pain severe enough to go to the emergency room. They determined he had a "hot" appnedix, and he underwent surgery. A few weeks later, when presenting with the same abdominal pain and vomiting after meals, they recommended having his gall bladder out, which he did.
Now, minus both an appendix and gall baldder, he continued to have abdominal pain and vomiting, and started to imagine the worst, stomach cancer, etc.
It was when refilling his prescription, the pharmacist commented, I can't believe he can take that much prilosec and still digest any food. You need SOME acid for digestion. Seems like he would have extreme abdominal pain and vomit up the undigested food!!---Thank-you Mr. Pharmacist!!!!
He stopped the prilosec, and cancelled his next appt for scoping to look for esophagus, stomach blockages, etc.
I would encourage everyone taking medications to ask their pharmacist to review all medications in relation to any new symptoms they might have. Sometimes a medication, or combination of medications may be causing the "new" problem.
I will repeat that since being on cpap, my husband no longer suffers reflux,
When he reported continued reflux to the Dr. he referred him to an internist and suggested he increase his Prilosec. The next day, the internest suggested he increase his Prilosec.
Now having tripled his prilosec intake, he began having abdominal pain and vomiting, with pain severe enough to go to the emergency room. They determined he had a "hot" appnedix, and he underwent surgery. A few weeks later, when presenting with the same abdominal pain and vomiting after meals, they recommended having his gall bladder out, which he did.
Now, minus both an appendix and gall baldder, he continued to have abdominal pain and vomiting, and started to imagine the worst, stomach cancer, etc.
It was when refilling his prescription, the pharmacist commented, I can't believe he can take that much prilosec and still digest any food. You need SOME acid for digestion. Seems like he would have extreme abdominal pain and vomit up the undigested food!!---Thank-you Mr. Pharmacist!!!!
He stopped the prilosec, and cancelled his next appt for scoping to look for esophagus, stomach blockages, etc.
I would encourage everyone taking medications to ask their pharmacist to review all medications in relation to any new symptoms they might have. Sometimes a medication, or combination of medications may be causing the "new" problem.
I will repeat that since being on cpap, my husband no longer suffers reflux,
It's interesting that the symptoms of too much acid are the same as not enough, and how a Dr. will immediately push the PPI's down your throat before investigating the cause of the stomach upset.It was when refilling his prescription, the pharmacist commented, I can't believe he can take that much prilosec and still digest any food. You need SOME acid for digestion. Seems like he would have extreme abdominal pain and vomit up the undigested food!!---Thank-you Mr. Pharmacist!!!!
Even more interesting is how they are quick with the knife, ready to cut out peoples organs without knowing for sure that the surgery is necessary.
What they did to your husband is borderline malpractice !
Trying is the first step towards failure.
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