Muffy Invented CPAP!

jnk wrote:I don't think the question is, ''Who invented pressure?' or, 'Who invented air?' or, 'Who invented breathing?' or, 'Who invented machines?' or anything like that. It seems to me that the question has to be: "Who first scientifically documented the application of pressure to the airway during sleep to stint it open as a medical treatment for sleep-disordered breathing in the form of obstructive sleep apnea?"

While it would be tempting to say GA Gregory or JT Wung, the earliest reference that I can find to anything resembling obstructive sleep apnea (central would another matter)(and there's a fair amount of leeway in re: "sleep" in neonates), I'm going to go with PM Dunn (1974), who did observe "inspiratory retractions" treating RDS neonates with the "Gregory box".

http://www.ncbi.nlm.nih.gov/pmc/article ... 3-0027.pdf

Muffy

Muffy wrote:

jnk wrote:I don't think the question is, ''Who invented pressure?' or, 'Who invented air?' or, 'Who invented breathing?' or, 'Who invented machines?' or anything like that. It seems to me that the question has to be: "Who first scientifically documented the application of pressure to the airway during sleep to stint it open as a medical treatment for sleep-disordered breathing in the form of obstructive sleep apnea?"

While it would be tempting to say GA Gregory or JT Wung, the earliest reference that I can find to anything resembling obstructive sleep apnea (central would another matter)(and there's a fair amount of leeway in re: "sleep" in neonates), I'm going to go with PM Dunn (1974), who did observe "inspiratory retractions" treating RDS neonates with the "Gregory box".

http://www.ncbi.nlm.nih.gov/pmc/article ... 3-0027.pdf

Muffy

Rats! I should have added "home/portable application" and "adults." More proof I would make a lousy patent attorney.

BTW, JT Wung, down there at Columbia, is the REAL "Father of (Bubble) CPAP", coming out with nasal prongs in the early 70's and dispensing with the "box" of the "Gregory box".

Muffy

jnk wrote:I don't think the question is, ''Who invented pressure?' or, 'Who invented air?' or, 'Who invented breathing?' or, 'Who invented machines?' or anything like that. It seems to me that the question has to be: "Who first scientifically documented the application of pressure to the airway during sleep to stint it open as a medical treatment for sleep-disordered breathing in the form of obstructive sleep apnea?" But maybe that is just a type of medical-machine-chronology gerrymandering, or something. I should have been a patent lawyer! (Except, of course, that I don't know anything about patents, medical machines, or the law. But other than that . . . !)

jeff

JNK

But, you sure know how to frame the really pertinent question.

DSM

Re who invented CPAP, and allowing for the wide deviation in intent of some of the referenced inventions, I will posit that in fact Leonardo Da Vinci is a good a candidate as any to lay claim to the modern cpap.

He recognized that in certain environments men needed pressurized air to keep their respiration going. If they didn't maintain a Continuous Positive Airway Pressure in these particular environments their airways would close up & they would gasp & splutter and stop breathing which of course tended to prove fatal. The environment he started with was under water. There are some claims he only copied ideas borrowed from the Chinese (1400s) and also that Aristotle had long ago (4th century BC) described the very invention Leonardo is credited with.

Later, the much more modern 'diving bell' style CPAP was invented and used right up to modern times. In fact all cpaps are merely variations of this design allowing for environment used in, and size of the mask , and size of the blower.

Franz Kessler in approx 1616 had a 2 man CPAP for use in wet environments. As can be imagined, it was a very cumbersome unit and had a very high mortality rate. The later improvement (see below) occurred around the 1800s and had a very effective blower but it was manual and thus not practical for home use by then OSA sufferers.

Below is the 1800s variation of the Leonardo design.

Glad I have been able to set the record straight

DSM



PS there are those who may argue that Guglielmo de Lorena actually should be given the credit over Leonardo, but we can debate that later. Who ever heard of de Lorena anyway. I mean just because one of his heirs (who altered his name slightly on migrating to the US) provided a prop for the movie back to the future II, doesn't mean he should block the light shining on Leonardo



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This may be the original Kessler model. As you can see, no use whatsoever for home titration.




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To further muddy the CPAP waters (so to speak) the below image records known records of Alexander the Great (reputed as having been a severe OSA sufferer (it killed him in the end)) being treated in his own personal cpap machine.





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Please feel free to google any of the above well established details

jnk wrote:

Muffy wrote:

jnk wrote:I don't think the question is, ''Who invented pressure?' or, 'Who invented air?' or, 'Who invented breathing?' or, 'Who invented machines?' or anything like that. It seems to me that the question has to be: "Who first scientifically documented the application of pressure to the airway during sleep to stint it open as a medical treatment for sleep-disordered breathing in the form of obstructive sleep apnea?"

While it would be tempting to say GA Gregory or JT Wung, the earliest reference that I can find to anything resembling obstructive sleep apnea (central would another matter)(and there's a fair amount of leeway in re: "sleep" in neonates), I'm going to go with PM Dunn (1974), who did observe "inspiratory retractions" treating RDS neonates with the "Gregory box".

http://www.ncbi.nlm.nih.gov/pmc/article ... 3-0027.pdf

Muffy

Rats! I should have added "home/portable application" and "adults." More proof I would make a lousy patent attorney.

Well, I would respectfully submit that the resulting introduction would become a little cumbersome:

"I would like to introduce ****, who first scientifically documented the application of pressure to the airway during sleep to stint it open as a home/portable application medical treatment for sleep-disordered breathing in the form of obstructive sleep apnea in adults. Let's give him a big round of applause."

Further, that's not what that boy over there built. He made a simple CPAP generator for patients who are intubated or have tracheostomy tubes, as evidenced by the patient connector:



There's no way they could have OSA, so that apparatus, as shown, does not represent a treatment modality for "sleep-disordered breathing in the form of obstructive sleep apnea in adults"; the phenomenon of xPAP had already been around about 40 years; could not be used in the home because it requires high pressure (50 PSI) air and oxygen sources; and every ICU HCP who could take time off from saying ridiculous/idiotic/hilarious things to their patients was already using an "H-valve" apparatus (which is what that thing really is) in treating ARDS.

Muffy

It reminds me of the first-to-fly arguments. People had been going airborne since time began, and the Wrights didn't invent the 747. But credit, in my opinion, should still go to Orville and Wilbur, those whose scientifically documented work had the biggest influence on what turned out to be the most practical approach. And that is so despite what the textbooks say in France and Brazil about the 'Father of Aviation.'

Similarly, although hospital treatments for breathing problems may have been around a long time, and many significant changes to the technology of home CPAP have occurred, still it is the guy whose work most contributed to my having a PAP machine next to my bed all night for my OSA that is the guy to whom I'd like most to give a professional pat on the back, whether that is Colin or Muffy or someone else.

jeff

jnk wrote:... still it is the guy whose work most contributed to my having a PAP machine next to my bed all night for my OSA that is the guy to whom I'd like most to give a professional pat on the back, whether that is Colin or Muffy or someone else.

Well, why didn't you say so?

That one's easy!

jnk wrote:And I am very thankful to my wife for telling me what I was doing, since I would never had known what I was doing in my sleep without her being there to tell me.

viewtopic.php?f=1&t=33359&p=283171&hilit=+wife#p283171

Muffy

Muffy wrote:

jnk wrote:... still it is the guy whose work most contributed to my having a PAP machine next to my bed all night for my OSA that is the guy to whom I'd like most to give a professional pat on the back, whether that is Colin or Muffy or someone else.

Well, why didn't you say so?

That one's easy!

jnk wrote:And I am very thankful to my wife for telling me what I was doing, since I would never had known what I was doing in my sleep without her being there to tell me.

viewtopic.php?f=1&t=33359&p=283171&hilit=+wife#p283171

Muffy

Perfect. Thanks for that.

Once again, Muffy takes the cake!

jeff

jnk wrote:

Perfect. Thanks for that.

Once again, Muffy takes the cake!

jeff

Laughing, too!!
That really was perfect!!!

Marveling at how Muffy found that.

Oh, ye of little faith, RG! Our Muffy can find anything! Like St Anthony.

rested gal wrote:Marveling at how Muffy found that.

I have a sneaking suspicion that Muffy has been keeping records on all of us--which I guess I should find disturbing, but somehow, instead, I find oddly comforting.

I'm pondering whether the polio iron lung would act like a cpap.

But I suppose it doesn't as the head and neck are outside the low pressure area.

... come to think of it, if you were totally enclosed in the iron lung and had a mask and tube connected to the outside atmosphere, that would work.

But I don't think it'll take off as a replacement for cpap!

snnnark wrote:I'm pondering whether the polio iron lung would act like a cpap.

Since it still employs a negative-pressure breathing system, it would not, and probably make things worse since it is not synchronized to respiration and you would probably miss the vasodilating effect of inspiration.

Muffy