Bye bye, zopiclone

General Discussion on any topic relating to CPAP and/or Sleep Apnea.
tetragon
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Bye bye, zopiclone

Post by tetragon » Mon Jan 07, 2013 7:27 pm

At my latest sleep doctor appointment, the doctor decided to try zopiclone, to see if it would keep me asleep.  While I am not a fan of the side effects and having that sleepy, fuzzy feeling of just waking up in the middle of the night through to mid-afternoon, the Zeo numbers from last night are rather uncharacteristic.

Last night:
ZQ: 80
Total sleep: 7:25
Sleep latency: 0:14
Times woken: 4
Wake: 0:04 (1%)
REM: 1:26 (19%)
Light: 4:55 (66%)
Deep: 1:05 (14%)
2012-12-18 (of the recent, recorded nights, this has the closest sleep time):
ZQ: 73
Total sleep: 7:07
Sleep latency: 0:13
Wake: 0:34 (7%)
REM: 0:55 (12%)
Light: 4:48 (63%)
Deep: 1:24 (22%)
Image

Other uncharacteristic things include forgetting my toque at home, trying to lock my apartment open, and the aforementioned sleepy-fuzzy feeling.  I should probably hook up the computer again tonight, and try to remember to post a few graphs.

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Last edited by tetragon on Sat Mar 02, 2013 9:41 am, edited 2 times in total.

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Jay Aitchsee
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Re: What my Zeo thinks of zopiclone

Post by Jay Aitchsee » Tue Jan 08, 2013 7:57 am

That's interesting, Tetragon. I don't think zopiclone is available in the U.S., but I think it's closely related to Ambien and Lunesta. I have used ambien and it has produced the hangover effects you mention at the standard dose of 10mg. I have split the tabs to 5mg, still effective, but no hangover. The problem with Ambien is that its effectiveness seems to last only half the night. What about zopiclne?
You'll have to update us after you've taken it for a while.

J

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Tue Jan 08, 2013 11:35 am

What I'm taking is equivalent to 2.5mg of Lunesta. It has a rather long half-life (six hours), and was chosen specifically to avoid wearing off half way through the night (the point of it being to reduce my short awakenings). The pharmacist specifically warned off of driving and that I could sleep on the bus. I'm not paying much attention to that warning, though, as I was already taking the bus.

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Tue Jan 08, 2013 8:50 pm

And now for 2013-01-07:
ZQ: 79
Total sleep: 7:35
Sleep latency: 0:14
Times woken: 6
Wake: 0:13 (3%)
REM: 0:53 (11%)
Light: 5:28 (70%)
Deep: 1:14 (16%)
Image

And this set of data can be graphed. Looking at it on my computer, all I can tell is that it looks like something diced my deep sleep. The longest consecutive duration of what the Zeo considers to be deep was twelve minutes.

I really need to remember to get this stuff ready for posting.

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Last edited by tetragon on Thu Jan 10, 2013 4:55 pm, edited 1 time in total.

cosmo
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Re: What my Zeo thinks of zopiclone

Post by cosmo » Tue Jan 08, 2013 9:26 pm

Cool
Last edited by cosmo on Thu Jan 10, 2013 5:07 pm, edited 2 times in total.

patrissimo
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Re: What my Zeo thinks of zopiclone

Post by patrissimo » Wed Jan 09, 2013 12:47 am

I haven't done any computations on my zeo data yet, though I track what sleeping pills I take, but I know that subjectively all the Z-s give me crappy sleep. But I've used them a lot, making the "quantity over quality" mistake discussed in Sound Mind / Sound Body, because at least then I don't notice having apnea, and the awful nights go by fast, and I get to "sleep" quickly. But I know a lot of people who find the sleep just as refreshing.

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Wed Jan 09, 2013 5:10 am

So far, I haven't got the result I was hoping for of feeling rested. Instead I got something that seems to improve on one of the numbers that could cause not feeling rested (the number of times I wake up), along with a constant fuzzy-sleepy feeling and killing off my deep sleep. And I wouldn't mind it if my dreaming went back to normal. I prefered the less-dreaming thing I had going earlier. It's just too much. When I was given the prescription, I was told that it could improve things, or it could cause no changes or make things worse. How definite.

2013-01-08:
ZQ: 78
Total sleep: 7:21
Sleep latency: 0:18
Times woken: 7
Wake: 0:10 (2%)
REM: 1:32 (20%)
Light: 4:43 (63%)
Deep: 1:07 (1:07)
Image

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Thu Jan 10, 2013 5:08 am

I hate this stuff.  Too much fuzzy-sleepy, too much colliding with the scenery.  The only "good" that I have noticed is that I don't remember waking up as many times at night.  I know that my sleep doctor stated to try it for two months, but no, that's too long.  I've already spilt my blood as a result of it, over a sidewalk crack.  Or does that not count as it didn't actually stain the sidewalk, due to anti-winter clothing reducing sidewalk rash and soaking up what little blood was drawn?  Anyway, I want out of this twilight existence.  My doctor will probably bring up the appointment that led to this when I see her next week.

2013-01-09:
ZQ: 72
Total sleep: 7:06
Sleep latency: 0:09
Times woken: 8
Wake: 0:20 (4%)
REM: 1:03 (14%)
Light: 5:02 (68%)
Deep: 1:02 (14%)
Image

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Jay Aitchsee
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Re: What my Zeo thinks of zopiclone

Post by Jay Aitchsee » Thu Jan 10, 2013 6:22 am

tetragon wrote:2012-12-18 (of the recent, recorded nights, this has the closest sleep time):
ZQ: 73Total sleep: 7:07
Sleep latency: 0:13
Wake: 0:34 (7%)
REM: 0:55 (12%)
Light: 4:48 (63%)
Deep: 1:24 (22%)
I don't know, these numbers didn't look too bad to begin with. A little light on REM, maybe.
J

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Thu Jan 10, 2013 7:01 am

Jay Aitchsee wrote:I don't know, these numbers didn't look too bad to begin with. A little light on REM, maybe.
My in-lab numbers do tend to be a bit higher in WASO, somewhere around 1.5h (22%-ish, I don't yet have numbers in any precision better than hours) in my latest study. The intent was to cut down on short awakenings and possibly the arousals. If I remember, I'll add in some of the graphs later today.

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Thu Jan 10, 2013 5:04 pm

A few graphs have been added.

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Re: What my Zeo thinks of zopiclone

Post by Jay Aitchsee » Thu Jan 10, 2013 6:33 pm

Have you compared your leak line to your Zeo as here: viewtopic/t85631/Leaks-Apneas-and-Distu ... ml#p779055
Leaks, even ones that are not too severe seem to interupt my Deep Sleep. Lately, my deep has been really fractured by leaks that I haven't been conscious of so that my Zeo reports are looking a lot like yours.
Jay

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Thu Jan 10, 2013 8:46 pm

I don't normally bother, as my leak line tends to be very tightly constrained, more so than on your good night. This trend has been continuing over the past few nights.

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Re: What my Zeo thinks of zopiclone

Post by Jay Aitchsee » Fri Jan 11, 2013 7:51 am

Just a thought.
J

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tetragon
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Re: What my Zeo thinks of zopiclone

Post by tetragon » Fri Jan 11, 2013 7:37 pm

That thought is part of why I started wearing a chin strap after a dentist started adding nocturnal hardware that stops me from being able to close my mouth normally at night. Most of the time, the opening is not be sufficient to cause a leak, but there have been a few occasions when I woke to the horrible sound of mouth leak. There are so many different things that can disrupt a night.

Anyway, last night's leak was constrained to the range 21 - 26, where 26 was only reached momentarily. Also notable was that towards the end of the night, CPAP-Check decided to return my pressure to 9.5 from the 10.5 it was for the past month.

2013-01-10:
ZQ: 69
Total sleep: 6:22
Sleep latency: 0:17
Times woken: 4
Wake: 0:05 (1%)
REM: 0:44 (11%)
Light: 4:30 (70%)
Deep: 1:08 (17%)

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