Since you are already using a higher pressure by allowing APAP to adjust upwards anyway there really isn't any danger in increasing the minimum. Probably the worse thing that might happen would be a little aerophagia but that is unlikely since you are already using higher when the pressure increases anyway ...and you didn't mention any aerophagia issues.
Several reasons why we suggest to go up slowly...one being simply comfort and ease in to the adjustment with starting out with a little more pressure than what you are used to. It's and easier adjustment going in 0.5 cm or 1.0 cm increments than it is to be taking any big jumps. In your case I don't even think a big jump would be needed but if it were I would still say to take it slow because of the 2nd reason we suggest to go slowly...sometimes we don't need as much more pressure as we might initially think.
I would be really surprised if you needed any more than 2.0 cm to clean up those clusters...and my gut says that 1.0 cm would probably be the most you might need.
My OSA is worse in REM sleep so I have first hand experience seeing clusters similar to yours. Since you doubt that you do much back sleeping and since the clusters appear to be within a time frame where we might expect to be in REM sleep...I am betting that you are like me in that sometimes REM sleep just seems to produce more stubborn OSA events. Doesn't happen in all REM stages but sometimes just some REM stages. I never could figure out why I didn't see the pressure spikes in all REM stages or why some nights I didn't have any spikes.
I think I have a report that I could share with you that shows what I am talking about. Sometimes pictures help.
Your 5 cm pressure is really relatively low...going to 6 or 7 (which I doubt the 7 is technically needed) isn't going to hurt anything and might just help and wouldn't hurt to try.
Here in this thread I talk about my clusters when I was figuring out what pressures to use.
viewtopic.php?f=1&t=88508&st=0&sk=t&sd= ... ster+child
I think it is the second image in my first post.
If you go here you can see a hypnogram that shows the normal sleep cycles and when we can expect REM...look on the right side and scroll down just a bit to see it.
http://en.wikipedia.org/wiki/Sleep
I suspect that you are probably in a more prolonged REM stage sleep when you see those 3 AM clusters and just need a little more baseline (that minimum pressure) to help the machine do a little better job.
The other alternative if it's the pressure changing itself that is disturbing your sleep would be to go with a fixed cpap pressure but you would need to use up around 10 or maybe more all night and you might not like that as much.
I would try easiest and simplest first if it were me and that would be just a little more minimum pressure and see what happens.
Cross the "use fixed pressure" bridge only if we need to but keep that idea on the back burner.
I may have to RISE but I refuse to SHINE.