Pharmacological Treatment of Obstructive Sleep Apnea with a

[roster]

Pharmacological Treatment of Obstructive Sleep Apnea with a Combination of Pseudoephedrine and Domperidone

http://www.aasmnet.org/jcsm/ViewAbstract.aspx?pid=27758

Looks like a schlocky study. Eh?

[Slinky]

I'm quite sensitive to medications. I prefer the "inconvenience" of PAP therapy to the "risk" of pharmaceuticals, thank you.

[rosiefrosie]

I'm quite sensitive to medications. I prefer the "inconvenience" of PAP therapy to the "risk" of pharmaceuticals, thank you.

Same here!

[oscar98]

Looks like a schlocky study. Eh?

So if I read this right their only means of measuring the sleep apnea was to rely on the patients report of rather or not they were snoring or having apneas. How many of us are aware of our apneas when they occur???

I would tell you that my cpap treats my apnea 100% as I have no recollection of having any. The data on my machine says otherwise. So yeah I'd say this study left a little something to be desired. I also like how it says the patents had less daytime sleepiness during the study. Who wouldn't after being doped up with pseudoephedrine.

[park_ridge_dave]

Looks like a schlocky study. Eh?

So if I read this right their only means of measuring the sleep apnea was to rely on the patients report of rather or not they were snoring or having apneas. How many of us are aware of our apneas when they occur???

I would tell you that my cpap treats my apnea 100% as I have no recollection of having any. The data on my machine says otherwise. So yeah I'd say this study left a little something to be desired. I also like how it says the patents had less daytime sleepiness during the study. Who wouldn't after being doped up with pseudoephedrine.

OK so I looked up the compounds. Pseudoephedrine essentially a decongestant that is also a stimulant and Domperidone (which is not approved for sale in the US ) which is essentially an Antiemetic (or also a lactation enhancer ). So I asked myself, why not some Calritin or Sudafed with a Pepto-Bismal Chaser

Or just give 'em No-Doz that'll "pep 'em up"

Unbelievable, who funded the study Janssen Pharmaceutical? Or did these guys just "dash off" the study between meth cooking sessions?

Cheers,

Dave

[oscar98]

Or did these guys just "dash off" the study between meth cooking sessions?

Cheers,

Dave

Being from the middle of farm country that was also my first thought.

[newhosehead]

Or did these guys just "dash off" the study between meth cooking sessions?

Cheers,

Dave

Being from the middle of farm country that was also my first thought.

Oscar, Middle of farm country here too, that was my first thought as well.

Jeanette

[wil]

I know when I pop a Sudafed and a bottle of DomPerignon I sleep like a baby...

Maybe that's not what they mean....

[brazospearl]

This is such nonsense. Of course these people didn't feel as sleepy on speed. That's kinda the point of the stuff, isn't it? Not feeling as sleepy doesn't necessarily = no apneas.

We're surrounded by morons, I swear.

[Mnementh]

The one thing in this that might lend it some credence is the oximetry readings. If the oxygen saturation is not going down, that's an indication you're still breathing normally. If I'm reading it correctly, this states that the levels in the majority of these test patients did not go down, but improved. I'm not sure why they couldn't just do a sleep study and get the actual AHI for these people, and that may be whats next for it. Should have been what's first for it, but you don't get more grant money by irresponsibly staying under budget!

If all it does is take away the daytime sleepiness, the Nuvigil my doctor prescribed does that just fine, with no side effects.

[BlackSpinner]

Pharmacological Treatment of Obstructive Sleep Apnea with a Combination of Pseudoephedrine and Domperidone

http://www.aasmnet.org/jcsm/ViewAbstract.aspx?pid=27758

Looks like a schlocky study. Eh?

Way back in 1990 the doctor prescribed antihistamines for my snoring - it didn't help one bit.