Use of Otrivine... I stopped and AHI dropped.

[bjhughes]

oxymetazoline products, I used it for many years on a daily basis

These researchers concluded that long-term use led to ... long-term use.

The authors concluded that long-term use of oxymetazoline induces a sensation of nasal stuffiness, which may be due to unconscious exaggeration of the degree of nasal stuffiness, induced nasal hyperreactivity, or a combination of both.

https://www.ncbi.nlm.nih.gov/pubmed/8628089

I already experienced nasal hyperreactivity long before using it and it was of great use in keeping my sinuses open; I was a heavy mouth-breather in my teens, much to my fellow student's enjoyment. For me any downsides to Afrin were a minor consideration vs. the alternatives of mouth-breathing and poor sleep due to being heavily stuffed up or using Benadryl and falling asleep during the day.

[ChicagoGranny]

For anyone else reading, a consultation with an ENT would be wise before beginning a years-long, daily usage of oxymetazoline.