Numerous research studies seem to suggest that melatonin should be used only temporarily, at a low dose generally, and probably for few ailments. Chronic insomnia appears to be excluded, for instance. The substance was reported to release certain stress hormones, induce inflammation in some medical ...

A dose as low as 0.5mg has been shown to interfere with the metabolism. Melatonin has both an anti- as well as a pro-oxidant potential. Probably depending on its dose, the age of an individual, the health status of a person, and other considerations. It surely isn't the harmless substance some peopl...

The conventional perspective on melatonin (and serotonin and tryptophan) is that they are safe and good for sleep. A perusal of a number of different lines of research, however, reveal that they all pose some rather distressing side effects, ranging from brain dysfunction/degeneration, muscle pain, ...