These runaway aberations are killing me!

General Discussion on any topic relating to CPAP and/or Sleep Apnea.
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plr66
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These runaway aberations are killing me!

Post by plr66 » Mon Dec 29, 2008 6:38 pm

I need some help with this, please. What might be going on with the escalations in pressure shown on these two reports? This pattern has happened to me about 4-5X in the past 4 months, and I am completely wrecked the next day. This is in such stark contrast to my typical night of AHI averaging between 1.2-2.4 or so, with leak rate being at about 33 with my Swift LT.

The first (12/16/08) happened when I was asleep, and with setting of 10.5/20 Apap with no flex, HH set at 1.0, as has been usual for me for 3 months. No unusual events prior to bed, good sleep hygiene as far as routines go. Got up--no, actually was finally blown out of bed!, went to the bathroom, and all was okay after that (except leak rate higher than usual on return to bed). What's causing what here?

Image[/img]


After that night, I decided to set my max pressure at 16 to hopefully avoid the runaway thing from going out of control to the top and waking me. Well last night was the worst night I have had since I brought home my first Cpap machine! OMG. Although the line didn't print well in the report shown below, the pressure remained at the max of 16 for the entire last 1.75 hours. Woke up at 4AM, had sweats for first time for 4 months, and was awake for every bit of that last 2 hours. No bad dreams, no anxiety, nothing unusual about my sleep routine. I am totally blown away by the number of OA's during that 2 hours, but am aware that I really don't know how to interpret such events when in an awake state. Is it all to be disregarded? But if so, can you all help me figure out what is causing such scenarios?

Image[/img]
Last edited by plr66 on Tue Dec 30, 2008 7:41 pm, edited 1 time in total.
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ozij
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Re: These runaway aberations are killing me!

Post by ozij » Mon Dec 29, 2008 10:25 pm

Disregard and ignore anything that happened when you were awake - the machine is incapable of understanding your breathing patterns when you're tossing and turning, and anything it reports about that time is truly meaningless.

Automatic machine base their identification of a breathing disturbance on analysing the previous breaths. When there's nothing stable to comparte to, that identification is wrong. Its as though you were trying to undestand a person talking to you through the noise of jet planes taking off while your both standing on the runway - can't be done.

The more difficult question is what causes that unlimited rise in pressure which wakes you up in the first place.
I don't know.

Can you give us more info about your PSG? Did you sleep deep enough for them to recommend a pressure, and if so, what was it?

What pressures did you try on the 420E? You can tell the 420E to limit it's pressure on response to apnea - something you can't do with the Remstar. The Respironics Remstar auto algorithm is very bad at identifying pressure induced apneas - and you can suddenly find it raising the pressure uncontorllably in response to those. How did you choose the max. pressure on your machine?

Since you do have a 420E, if it were me, I would switch to that to find out what was going on with my breathing.
I would set its "maximum pressure for command on apnea" to equal the the fixed pressure recommended by the PSG, or the maximum pressure - if you had a range recommendation. That way, it would not supply more pressure in response to apneas - even if it thinks they are obstructive; It may make the wrong identification, but you can keep it from raising the pressure.


O.

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Re: These runaway aberations are killing me!

Post by Wulfman » Mon Dec 29, 2008 10:47 pm

Your best AHI seems to be at a pressure of 10. Why let it go any higher?

Den
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Re: These runaway aberations are killing me!

Post by Goofproof » Mon Dec 29, 2008 11:12 pm

Wulfman wrote:Your best AHI seems to be at a pressure of 10. Why let it go any higher?

Den
Ditto, it's foolish to let a APAP go to 20. Most of your data is useless, I wouldn't be trusting it. 10 to 15 cm range or lower the top even more. Also leaks, Tape to control or use a FF mask, Leaks first then pressure. The machine can only read sleeping patterns, and then only if leaks are under control. Jim
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plr66
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Re: These runaway aberations are killing me!

Post by plr66 » Tue Dec 30, 2008 6:07 pm

Thanks so much for these responses, folks. I'm just getting home from work to be able now to respond. Den, I've not just set a straight cpap pressure of 10 because I guess I figured that the whole purpose of an Apap is so that the machine can increase pressure as appropriate. I did decrease the max from 20 to 16, hoping to stop these crazy runs...
And Jim, I've been taping from the start, and have always and consistently had leaks under excellent control (except when the apap goes wild like this up to max pressure).

Thanks for setting me straight about the waking data being garbage.
ozij wrote:Can you give us more info about your PSG? Did you sleep deep enough for them to recommend a pressure, and if so, what was it?
Yes, I believe there was no indication that they had any trouble gathering sleep data at my study. Not sure how to know if I had sleep "deep enough." They noted that my events were more evident in REM sleep. Recommended pressure was 8. I gradually increased that after the first month of having AHI's consistently around 5--just experimenting to see if I could get that down. And it was effective to do so. I began that increase to 10 just after I traded my cpap for an apap Remstar after the first month. Only had one of those runaway nights on the Remstar during the first 2 months of therapy.
ozij wrote:What pressures did you try on the 420E? You can tell the 420E to limit it's pressure on response to apnea - something you can't do with the Remstar. The Respironics Remstar auto algorithm is very bad at identifying pressure induced apneas - and you can suddenly find it raising the pressure uncontorllably in response to those. How did you choose the max. pressure on your machine?
When I got my backup 420E, I set it to 10 - 20 just as I had with the Remstar apap. No reason at all that I chose 20 as the max. Just didn't see that it should make any difference, since I unfortunately did not understand the possibility of this "chasing" thing. The first night was my education about needing to turn my IFL1 off...after getting blown into the next county.
ozij wrote:Since you do have a 420E, if it were me, I would switch to that to find out what was going on with my breathing.
I would set its "maximum pressure for command on apnea" to equal the the fixed pressure recommended by the PSG, or the maximum pressure - if you had a range recommendation. That way, it would not supply more pressure in response to apneas - even if it thinks they are obstructive; It may make the wrong identification, but you can keep it from raising the pressure. O.
Ozi, is this the same thing as setting the minimum & max pressure to the same setting using apap on the Remstar? Not sure I know how to set "maximum pressure for command on apnea" on the 420E. Will there be a way to interpret what's going on to cause these runaway episodes?

Can't tell you all how much I value your wisdom! Thanks again for the patience.
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Re: These runaway aberations are killing me!

Post by mindy » Tue Dec 30, 2008 6:17 pm

I had a similar problem with the Respironics - when I tried APAP mode with a range, my pressure and AHI were a moving target. I finally got really frustrated with it and started with a fixed pressure 8 and then increased by 1 each week. I kept seeing improvement and when I hit 13, it was looking pretty good. Then I tried 14 and it seemed like the world went crazy - AHI went way up. So I set it at 13 CPAP mode and it worked reasonably well.

With the Sandman, I had some problems with pressure until I turned IFL off. Now my pressure stays around 8-9 and my AHI is reasonably low.

The "maximum pressure for command on apnea" is among the rest of the settings and seems to work for me.

I, too, went through a period of time (on the Respironics) fighting setting a single pressure "because it was an APAP". However, a better way to look at it (imho) is that the APAP has the greatest flexibility for tailoring therapy and that includes setting a single pressure. It also makes it possible to do a "mini" sleep study if we think things have changed.

Mindy

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Re: These runaway aberations are killing me!

Post by CorgiGirl » Tue Dec 30, 2008 6:33 pm

I had the same problem with the first M series, but the second I got doesn't do it. I think you may be having a malfunction and I'd see about getting it exchanged or repaired or reprogrammed or whatever it is that DME's do with malfunctioning units.... Good luck!

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Re: These runaway aberations are killing me!

Post by mindy » Tue Dec 30, 2008 6:41 pm

It was explained on this forum that some people react this way to higher pressure (ref restedgal, ozij and others).

m

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Re: These runaway aberations are killing me!

Post by Wulfman » Tue Dec 30, 2008 7:21 pm

plr66 wrote:Den, I've not just set a straight cpap pressure of 10 because I guess I figured that the whole purpose of an Apap is so that the machine can increase pressure as appropriate.
Unfortunately, that's what too many people think about the Autos/APAPs. Or......"I paid all this extra money for an Auto and I NEED to use it that way."

The APAPs/Autos are "versatile" machines (and data-capable). They have more modes than straight CPAPs, but the point I keep trying to get across is that having a versatile machine is only PART of the equation......the other (or another) part is that the user has to experiment and recognize what works best for them. "Auto" doesn't mean that it is AUTOMATICALLY the "best" therapy. It only means that it will auto-adjust to events.....some of which is not desirable.

Den
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Re: These runaway aberations are killing me!

Post by plr66 » Tue Dec 30, 2008 7:49 pm

Wulfman wrote:Your best AHI seems to be at a pressure of 10. Why let it go any higher?

Den
Den, I need to come back to this question. When I looked at that second report, it appeared to me that I began having OA's which triggered a slight increase in pressure....and the OA's continued, so the auto pressure responded to try to correct this....and on & on (not sure at what point I was awakened by the annoyances). So I'm trying to interpret this. What is causing what? And if I set my machine to straight cpap at 10, and begin to have a bunch of OA's, how will the apap be able to respond at all? Sorry if I seem dense, but I actually AM trying to use the apap to figure out what works and what's needed.
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Re: These runaway aberations are killing me!

Post by Wulfman » Tue Dec 30, 2008 8:23 pm

plr66 wrote:
Wulfman wrote:Your best AHI seems to be at a pressure of 10. Why let it go any higher?

Den
Den, I need to come back to this question. When I looked at that second report, it appeared to me that I began having OA's which triggered a slight increase in pressure....and the OA's continued, so the auto pressure responded to try to correct this....and on & on (not sure at what point I was awakened by the annoyances). So I'm trying to interpret this. What is causing what? And if I set my machine to straight cpap at 10, and begin to have a bunch of OA's, how will the apap be able to respond at all? Sorry if I seem dense, but I actually AM trying to use the apap to figure out what works and what's needed.
One thing you don't know is if the "pressure bumps" (regardless of whether they're the little ones or bigger increases) are not actually causing an involuntary resistance in your airway. My theory is that some of us feel the pressure increases and that causes the airway to resist more pressure.....then it interprets that as yet another reason to bump pressure.
Another point to remember is that of how the Respironics algorithm works.

http://sleepapnea.respironics.com/techn ... rithm.aspx

http://sleepapnea.respironics.com/techn ... apnea.aspx

It seems obvious that INCREASING pressure above a certain point may be creating more events......for whatever reason......and it's definitely not decreasing them. They're not showing up (with the exception of two on the second chart) as Non-Responsive (possible Centrals), so whether you're in REM or very deep sleep when they're occurring is not capable of being known from the data from these machines. There's some leakage going on at the same time, but that could be an issue with the pressure and mask adjustments.

I REALLY, REALLY think that you should TRY a fixed pressure of 10 cm. for a week and see what things look like.

This is a case where you may NOT want an auto to respond to some events.

Den
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Re: These runaway aberations are killing me!

Post by plr66 » Tue Dec 30, 2008 8:42 pm

Wulfman wrote:......It seems obvious that INCREASING pressure above a certain point may be creating more events......for whatever reason......and it's definitely not decreasing them. They're not showing up (with the exception of two on the second chart) as Non-Responsive (possible Centrals), so whether you're in REM or very deep sleep when they're occurring is not capable of being known from the data from these machines. There's some leakage going on at the same time, but that could be an issue with the pressure and mask adjustments.

I REALLY, REALLY think that you should TRY a fixed pressure of 10 cm. for a week and see what things look like.

This is a case where you may NOT want an auto to respond to some events.

Den
Thank you, Den. You know it had not even occurred to me that NR should have been registering here if the pressure increases were a result of that. Geesh. Where has my deductive reasoning gone~~~ Yes. I REALLY REALLY WILL try a fixed pressure of 10 for the next week!! Thanks.
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Re: These runaway aberations are killing me!

Post by Wulfman » Tue Dec 30, 2008 9:04 pm

The thing we don't know is.......if the increases are causing the events or if the events are causing the increases. I see lots more "blank space" (fewer events) when your pressure is staying on the minimum line. Leaks may be a marginal factor, too. But, by going "straight pressure" there are not as many variables to guess at.

Den
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Re: These runaway aberations are killing me!

Post by plr66 » Tue Dec 30, 2008 9:10 pm

Wulfman wrote:The thing we don't know is.......if the increases are causing the events or if the events are causing the increases. I see lots more "blank space" (fewer events) when your pressure is staying on the minimum line. Leaks may be a marginal factor, too. But, by going "straight pressure" there are not as many variables to guess at.

Den
Yes. And I am pretty sure that my leaking has been really well under control at the recommended level until these runs of escalating and maxed-out pressure occur. So I'll get to see if that's true as well.
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Re: These runaway aberations are killing me!

Post by ozij » Tue Dec 30, 2008 9:15 pm

plr66 wrote:
ozij wrote:Since you do have a 420E, if it were me, I would switch to that to find out what was going on with my breathing.
I would set its "maximum pressure for command on apnea" to equal the the fixed pressure recommended by the PSG, or the maximum pressure - if you had a range recommendation. That way, it would not supply more pressure in response to apneas - even if it thinks they are obstructive; It may make the wrong identification, but you can keep it from raising the pressure. O.
Ozi, is this the same thing as setting the minimum & max pressure to the same setting using apap on the Remstar? Not sure I know how to set "maximum pressure for command on apnea" on the 420E. Will there be a way to interpret what's going on to cause these runaway episodes?
Unlike a Respironics, you can give the 420E separate limits for apnea and snores. The 420E comes with a default limitation of 10 to its maximum response to apneas - but that can be changed if necessary. This flexibilty does not exits in either a Respironics or a Resmed. In your case - now that I know your pressures, I don't think you need to change it. You could set up the 420E to an initial pressure of 10, a minimum of 8 or 9 and a maximum of 16 - or 12, or whatever, and the machine would not respond to apneas that happen when your pressure is higher than 10 - but it would raise the pressure to the maximum if necessary should you snore, or have hypopneas accompanied by flow limitation.

I agree with Den's analysis -trying 10 fixed for a week may turn out to be good - and you'll know soon enough if it isn't. Granted, with your distinctly different breathing pattern in REM you may benefit from the flexibility to having more pressure part of the time - but maybe 10 is enough to handle your REM events as well - and you don't need the lower pressure since 10 is tolerable.

Nothihg will tell us why those runaway pressures happen. Working with the limited data we get from the machines, we're guessing - aiming at the best combination of numbers and quality of sleep and wakefulness.

The rather sudden appearance out of nowhere of the "mad machines syndrome" - two months without anything like that - make me think that CorgiGirl has a good point there too - have the machine checked. Luckily, you have a good backup machine.
Wulfman wrote:One thing you don't know is if the "pressure bumps" (regardless of whether they're the little ones or bigger increases) are not actually causing an involuntary resistance in your airway. My theory is that some of us feel the pressure increases and that causes the airway to resist more pressure.....then it interprets that as yet another reason to bump pressure.
Another point to remember is that of how the Respironics algorithm works.
I would say its the brain resisting - it stops breathing because of the info it get about how stretched the lungs are - so the airway is open, but breathing isn't taking place despite that - and that's the kind of non-breathing that will not respond to more and more and more pressure.

Taking into account the dialogue between Den you that is going on as I'm composing this, I would do the following:
Set up the 420E with max=min=10 -which will give you fixed pressure with all the enchanced reporting capacity of Silvelining.
Have the rogue behavior of the Respironics checked.

O.
O.

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