Generic Eszopiclone Problems

I have been taking generic eszopiclone 3mg since it first became available and haven't had a problem until I the pharmacy changed manufacturers to Orchid. The Orchid pill does not put me to sleep. I have had no problem with Teva manufactured eszopiclone. It works just like the original Lunesta. Within 30 mins of taking it, I'm asleep.
A year ago I was given Dr Reddys manufactured and it did not put me to sleep either.
So far the only generic that works for me is Teva. I have a flag on my account at the pharmacy that I prefer Teva but they apparently ran out of it last week!!? They gave me Orchid and I haven't had a good nights sleep since. I'm feeling so tired and depressed. It's really crazy to have an approved generic that doesn't work!!

Unless you are using a CPAP, you are in the wrong message board

File a complaint with the FDA.
Your pharmacy may be dispensing a COUNTERFEIT.

looks like guerrilla marketing spam to me.

"this brand is bad, buy the good brand instead"

Hmm, that too, I guess.

Cpaptalk to the rescue again.

I have not had a decent night's sleep in about a month, for no reason that I could see. I never thought to check my generic eszopiclone (although I've had similar issues with other drugs for other conditions.) I've been taking a generic made by Glen Mark, according to the label, and I have a bottle of a lower dose made by Dr. Reddy's. I know I've gotten Teva in the past. I'll talk to the pharmacist tomorrow and see if I can get some of that so I can compare.

I have apnea and use PAP, of course; that's why I'm here. But that's only one of the sleep disorders I have. (I have them all - ) Thanks to PAP, the little sleep I get is good, and uninterrupted, but it doesn't make me sleep and it wasn't designed to. I can't be the only one here with insomnia that interferes with getting PAP's full benefit. Thanks; this was good information for me.

QueSera wrote:Cpaptalk to the rescue again.

I have not had a decent night's sleep in about a month, for no reason that I could see. I never thought to check my generic eszopiclone (although I've had similar issues with other drugs for other conditions.) I've been taking a generic made by Glen Mark, according to the label, and I have a bottle of a lower dose made by Dr. Reddy's. I know I've gotten Teva in the past. I'll talk to the pharmacist tomorrow and see if I can get some of that so I can compare.

I have apnea and use PAP, of course; that's why I'm here. But that's only one of the sleep disorders I have. (I have them all - ) Thanks to PAP, the little sleep I get is good, and uninterrupted, but it doesn't make me sleep and it wasn't designed to. I can't be the only one here with insomnia that interferes with getting PAP's full benefit. Thanks; this was good information for me.

Hi, this is interesting to me too. Last year a doctor gave me a prescription for Lunesta but the pharmacy gave me the generic eszopiclone. Most likely my insurance wouldn't pay for Lunesta, very expensive. So this year I was having an especially hard time sleeping in June with the hot weather settling in and who knows what else. So I decided to try the generic stuff rather than increase my dose of clonazepam. My God, the 2mg pill kept me awake almost all night, felt horrible the next day. Needless to say, I got rid of the stuff so I wouldn't forget and take it again. I don't like to mix drugs at all anyway so I think it was for the better. I just looked up eszopiclone on drugs.com and see more complaints of all night insomnia. What in the world.

Chronic insomnia is another symptom of sleep apnea, you know that right? Doctors I saw apparently didn't know and it took years before an NP finally sent me to a sleep clinic. Just curious how long you had the insomnia before being diagnosed and what other sleep disorders do you have? I have restless legs, numbness, myoclonic jerks at sleep onset. Cpap has been helping me get rid of all this nerve stuff, especially since my sleep clinic switched me to variable pressure. I'm now taking a smaller dose of clonazepam and getting about 5.5 hrs sleep on cpap now. For the last three days I've felt fairly good on that. Hope it lasts. Is your AHI okay? With variable cpap pressure, my avg has decreased from 5 to less than 2 every night. I recently changed my aflex from 3 to 1 and maybe that helped.

I think the years of untreated sleep apnea damaged my nervous system and it may take many months to gradually recover. Maybe you can eventually get off the sleeping meds too.

I've been having an interesting night and morning. I substituted the Dr Reddy generic for the Glen Mark, and I slept. My PAP numbers were nice and low, and I know these are reliable results because I actually was asleep. (I double-checked my sleep time/quality with a fitness tracker sleep app I've used before, even before I got the PAP, and whose results my doctor has reviewed in the past.) I just called the pharmacy and they will have the Teva-made generic for me on Monday.

Mr. Rogers used to sing a body song that went "Everything grows together, because you're all one piece." The older I get, the more this becomes my twisted reality. Everything hurts together because I'm all one piece. I've had sleep issues all of my life, whether delayed sleep onset, restless legs, early waking, plmd, frequent awakening, sleep misperception ... the whole nine yards. My father had all of these at one time or another, too. (I always assumed that myoclonic jerks happened to everyone; I didn't know it was yet another sleep issue. Surprise!)

We see specialists, and each one treats us for our ills in his or her special area. Although this has worked out better for me than a kindly neighborhood G.P. would have, it means that the sleep issues (which, it turns out, are interconnected to EVERYTHING) have been treated by an internist, a rheumatologist, and a cast of thousands. The first step in the right direction was seeing a Pulmonologist who got me on the right asthma med, and then stepping next door to see his colleague, who ordered the sleep study, which found the apnea, which led to the PAP.

In a perfect world, I wouldn't take any medication at all, but that's not the world I happened to turn up in. I hate sleep medication on principle, but without it, I simply do not fall asleep at night. (I tried it for nearly six months last year, hoping my body would find its own sleep pattern. I slept from about 4 am to 6 or 7am most days, sometimes not even that.) I have other conditions that require medication, so I've had to make peace with it all.

Thanks, Sylvia, for bringing this up. I expect it to have a very tangible and positive result for me.

I agree that the OP is suspect to say the least, however, the post does raise a good point. Many people still believe that a generic drug equals the brand version, that all generics are the same as each other, and to the original brand. Not true, but especially for drugs that affect the brain or are "extended release" types (ask a person who is taking extended release pain medications for example). Just ask any psychiatrist and they can probably tell you nasty stories of people having to switch from a brand to a generic, and then many times later to another manufacturer of the generic drug. I have had to make these types of switches for a couple different drugs and the results can be not fun. My psychiatrists will not take any generic medications even though he has to pay out-of-pocket; he has seen too many bad reactions to generic medications. Below is a link to "CrazyMeds" for a fairly good description of the issues involved and explains exactly what meets the "same as" criteria. "CrayMeds" may sound like a odd place to get medication information, but I have been reading this site for several years and have always found it to be accurate and many times, very funny. Well worth the time looking around the site, you may come across a drug that you are taking such as a specific sleeping pill. Even if not taking anything today, you may still find some very well written information about drugs that you may have heard about.

https://www.crazymeds.us/pmwiki/pmwiki. ... edications

Good to know, thanks.