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Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 6:08 am
by blizzardboy
Muffy wrote:IYAM, I don't see where bb actually has anything that should be treated by flox. I mean, the GP goes, "Here, try these for a while and see what happens". What makes him qualified to dx and rx?
Hi Muffy, I first made contact with my GP through an Australian Government managed depression website, so I presume that she must have some special training or endorsement to assess and treat cases of moderate depression and anxiety. At the time, I filled out a series of questionnaires and it was determined that I was suffering from mildly depression and anxiety. On this basis my GP then prescribed me fluoxetine. My GP also then recommended that I undergo CBT and put me onto a most professional and well-informed therapist.
Muffy wrote:
blizzardboy wrote:The reality for me is that they have been profoundly helpful. My wife and I call them my happy tablets.
You could fire up the Bong, too, and get that effect. Are you treating depression or getting stoned?
We call them happy tablets because through the changes that the tablets brought in my mood and irritability we gradually became increasingly happier as a family. Certainly no subtle effect. CPAP therapy seems to now be taking us to another level of happiness. New ground is now being broken every week...

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 6:25 am
by blizzardboy
Muffy wrote:
Although we really need four of 'em:
  • Before any treatment
  • On effective xPAP
  • On therapeutic SSRI
  • On effective xPAP and therpeutic SSRI
And then repeat with otter-level fish consumption.
You know, on reading that form I realised how far I have come over the past few years as I remember some of the answers I would have given back when I was first assessed pre-treatment. If I do end up changing from fluoxetine I will use this form to keep an objective measure of any mental health changes I may encounter. Cheers,

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 6:26 am
by Muffy
blizzardboy wrote:..so I presume that she must have some special training or endorsement to assess and treat cases of mild depression and anxiety. At the time, I filled out a series of questionnaires and it was determined that I was suffering from mildly depression and anxiety. On this basis my GP then prescribed me fluoxetine.
I think you should make a timeline to account for all the treatment variables (including CBT) and within the graph chart HDS (OK, this ain't going to be real scientific). But just look how much destroyed sleep will influence HDS, and if your HDS is still pretty close to what it was (and looking at your sleep log, you have a fair amount of points to add in there) one could argue that it's sleep disruption > depression rather than the reverse.

Muffy

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 6:37 am
by blizzardboy
Muffy wrote:I think you should make a timeline to account for all the treatment variables (including CBT) and within the graph chart HDS (OK, this ain't going to be real scientific). But just look how much destroyed sleep will influence HDS, and if your HDS is still pretty close to what it was (and looking at your sleep log, you have a fair amount of points to add in there) one could argue that it's sleep disruption > depression rather than the reverse.
Or I could just come off fluoxetine and record HDS pre- and post-weaning. Does SSRI withdrawal syndrome have a half life?

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 9:27 am
by SleepingUgly
SleepingUgly wrote:BTW, I just read something about SSRIs increasing upper airway patency in NREM sleep...
http://www3.interscience.wiley.com/jour ... 1&SRETRY=0

p. 298 in:
http://books.google.com/books?hl=en&lr= ... &q&f=false

p. 394 in:
http://books.google.com/books?id=M4bS5q ... em&f=false

There were others that I can't find now...

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 10:40 am
by Muffy
SleepingUgly wrote:
SleepingUgly wrote:BTW, I just read something about SSRIs increasing upper airway patency in NREM sleep...
http://www3.interscience.wiley.com/jour ... 1&SRETRY=0

p. 298 in:
http://books.google.com/books?hl=en&lr= ... &q&f=false

p. 394 in:
http://books.google.com/books?id=M4bS5q ... em&f=false

There were others that I can't find now...
Probably "the other forum" from 5 years ago:

http://apneasupport.org/post-2529.html& ... apine#2529

Muffy

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 10:44 am
by unadog
On depression cures. I'd be careful before I accepted statistics on any potential cure.

Interesting article from the NY Times, by a psychiatrist who specializes in psychopharmacology:

"It turned out that antidepressants are, indeed, effective, because on average patients taking the pills showed a 40 percent drop in depression scores. But placebo was also a powerful antidepressant, causing a 30 percent drop in depression scores. This meant that about three-quarters of the apparent response to antidepressants pills is actually due to the placebo effect. "

http://www.nytimes.com/2010/04/25/magaz ... oir-t.html


In general, I think that inadequate sleep is such a major, systemic stressor, that it is next to impossible to determine a cause and effect relationship with many systemic and endochronological disorders: depression, pain, hypothyroid, etc. You really just need to follow a pragmatic approach: fix sleep as well as possible, then see what happens with the rest of the system over a period of months.


This is also an interestingarticle on sleep and depression:

http://opinionator.blogs.nytimes.com/20 ... ion&st=cse

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 10:54 am
by -SWS
Well, here's another interesting albeit slightly contentious thread discussing SSRI's as controversial:
viewtopic.php?f=1&t=33368&st=0&sk=t&sd=a

People on this message board seem to fall in three categories: 1) SSRI's are really good, 2) SSRI's are really bad, and 3) eh... take 'em if you need 'em. Put me down as category three.

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:09 am
by brain_cloud
unadog wrote:On depression cures. I'd be careful before I accepted statistics on any potential cure.

Interesting article from the NY Times, by a psychiatrist who specializes in psychopharmacology:

"It turned out that antidepressants are, indeed, effective, because on average patients taking the pills showed a 40 percent drop in depression scores. But placebo was also a powerful antidepressant, causing a 30 percent drop in depression scores. This meant that about three-quarters of the apparent response to antidepressants pills is actually due to the placebo effect. "
If you want to have a educated viewpoint on these things, you are going have to crack a book or something. Articles in magazines and newspapers don't cut it. That quote above wouldn't pass peer review. Amongst its other defects, it's moronic.

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:17 am
by jnk
-SWS wrote:Well, here's another interesting albeit slightly contentious thread discussing SSRI's as controversial:
viewtopic.php?f=1&t=33368&st=0&sk=t&sd=a

People on this message board seem to fall in three categories: 1) SSRI's are really good, 2) SSRI's are really bad, and 3) eh... take 'em if you need 'em. Put me down as category three.
Is there any way we can incorporate a poll on that into this thread? That might get us to number 1 that much faster!

jeff

ps-@ brain_cloud: Dude. Check your dosing. We're all incredibly ignorant morons. It's just a matter of degree.

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:24 am
by unadog
brain_cloud wrote:If you want to have a educated viewpoint on these things, you are going have to crack a book or something.
Feel free:

Daniel Carlat is an associate clinical professor of psychiatry at Tufts University School of Medicine and the publisher of The Carlat Psychiatry Report.

His book, “Unhinged: the Trouble With Psychiatry,” will be published in May

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:43 am
by jnk
Did anyone mention yet that we're at NUMBER 4!!!!

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:44 am
by unadog
Peer reviewed. Based on FDA data.

Prozac, the bestselling antidepressant taken by 40 million people worldwide, does not work and nor do similar drugs in the same class, according to a major review released today.

The study examined all available data on the drugs, including results from clinical trials that the manufacturers chose not to publish at the time. The trials compared the effect on patients taking the drugs with those given a placebo or sugar pill.

When all the data was pulled together, it appeared that patients had improved - but those on placebo improved just as much as those on the drugs.


http://www.guardian.co.uk/society/2008/ ... alresearch


The full study itself:

http://www.plosmedicine.org/article/inf ... ed.0050045

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:48 am
by Muffy
Mr. Brain_Cloud, please be considerate of the other posters and comply with forum rules, which clearly state

Image

so won't you please kindly GTF outta here?

Thank you very much for your cooperation.

Muffy

Re: CompSA, Hypoventilation, PLMs, Bradycardia and Hypotension?

Posted: Sun May 16, 2010 11:57 am
by brain_cloud
unadog wrote:
brain_cloud wrote:If you want to have a educated viewpoint on these things, you are going have to crack a book or something.
Feel free:

Daniel Carlat is an associate clinical professor of psychiatry at Tufts University School of Medicine and the publisher of The Carlat Psychiatry Report.

His book, “Unhinged: the Trouble With Psychiatry,” will be published in May
That sounds very scholarly, doesn't it?

The sine qua non for being able to evaluate anti-establishment efforts is a good grounding in the mainstream discipline. All too often, however, folks jump straight the stuff that backs up their favorite hobby-horse position.