Data Analysis & High Respiratory Rate

General Discussion on any topic relating to CPAP and/or Sleep Apnea.
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luciferin
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Data Analysis & High Respiratory Rate

Post by luciferin » Mon Feb 27, 2023 3:08 pm

Would anyone be able to take a few minutes to look over my data and provide any suggestions for optimization?

For some information on my case, I was diagnosed a couple of weeks ago with severe SA in lab. My AHI was 33, and my REM AHI was 60. I have a total of 16 minutes of REM sleep during the study, which lasted a total of over 7.7 hours. I have not had a titration study done, but I am likely to have one at some future date. But it's really expensive due to my deductible, I'm worried they won't tell me anything I don't already know.
I have an APAP that I received from a previous diagnosis from Lofta that showed borderline OSA (AHI 4.5 and RDI of 10) and they suggested a trial of 4-20 cm auto mode which I have since changed to 8-13 cm auto on my own. Higher than 13 and I wake up frequently during the night, and never reach the high respiratory rate moments that I associate with REM sleep. I have tried 8 CPAP mode and I also never see the elevated REM and I feel noticeably worse.

Some things that stick out to me that I'm hoping for feedback on:
  • Respiratory rate seems really high periodically. I feel much better on days where I have the high respiratory rate more often, so I've been associating it with increased REM sleep. I don't know how to anylize the data to tell if it's real.
  • The 2/25 data shows a cluster of OA events start at 4:55 AM despite being near my max pressure already. Any advice on if anything should be done to control events like this?
  • Is my flow limit at all an issue that something should be done about?
Just a note, the gap in my sessions on 2/24 is not treatment related. My family woke me up for something unrelated.
2/23/23
2/24/23
2/25/23
2/26/23

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robysue1
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Re: Data Analysis & High Respiratory Rate

Post by robysue1 » Mon Feb 27, 2023 6:11 pm

luciferin wrote:
Mon Feb 27, 2023 3:08 pm
Would anyone be able to take a few minutes to look over my data and provide any suggestions for optimization?

For some information on my case, I was diagnosed a couple of weeks ago with severe SA in lab. My AHI was 33, and my REM AHI was 60. I have a total of 16 minutes of REM sleep during the study, which lasted a total of over 7.7 hours.
So your untreated OSA is really bad. And it's really, really bad in REM. Probably bad enough to make it difficult for your body to get into REM and stay there long enough for the REM sleep to be beneficial.
Higher than 13 and I wake up frequently during the night, and never reach the high respiratory rate moments that I associate with REM sleep. I have tried 8 CPAP mode and I also never see the elevated REM and I feel noticeably worse.
What exactly do you mean here? And how are you attempting to quantify a "high respiratory rate moment" that you "associate with REM sleep".

Given the charts you posted over at SleepHQ, it doesn't surprise me that straight CPAP @ 8cm could make you feel worse than APAP @ 8-13cm: Your charts indicate that whenever the pressure drops close to 8cm, there are enough flow limitations for the machine to start increasing the pressure up towards the 12-13 cm range, and that most likely means that if the pressure were held at 8cm for any length of time, some (many) of those flow limitations would in fact deteriorate into hypopneas and apneas.
Some things that stick out to me that I'm hoping for feedback on:
  • Respiratory rate seems really high periodically. I feel much better on days where I have the high respiratory rate more often, so I've been associating it with increased REM sleep. I don't know how to anylize the data to tell if it's real.
Again, it's not really clear what you are talking about here. While Oscar shows a respiratory rate graph, SleepHQ does not. Yes, if you zoom in on the data in SleepHQ to show maybe 1 minute of flow rate data at a time, you can get a good estimate of the (moving) respiratory rate by counting inhalations. But I'm not at all sure that's what you are doing when you say you are looking for "high respiratory rate" periods.

While it's known that in a typical person's (decent) quality sleep, the respiratory rate is more variable and often a bit higher in REM, it's not like there's a dramatic increase in the number of breaths per minute. For example, on all of my various sleep studies over the years, my non-REM respiratory rate is listed as being in the 12-14 and 14-16 breaths per minute range and my REM respiratory rate is listed as being in the 12-18 12-16, and 14-16 ranges.

The upshot of this is: It's kind of difficult to definitively identify REM periods just by looking at the respiratory rate in xPAP data, but if you see periods of higher variability in the respiratory rate at roughly 90 minute intervals, then that can point to probable REM periods.

But you also have to add in this: Breathing in REM can also look sort of like wake breathing since wake breathing is also more variable than normal non-REM sleep breathing. And then any time you arouse enough to turn over in bed, that also can cause some variation in the respiratory rate as well the size of the individual inhalations. So trying to tease out so-called "Sleep-Wake-Junk" breathing (SWJ) from possible REM is another problem.

If you are genuinely interested in whether you are getting into REM, you may want to think about getting a smart watch or fit-bit type device that claims to be able to detect sleep stages. While these devices are far from 100% accurate, they do monitor changes in the heartbeat and lack of movement to attempt to flag REM; some of them also factor in measuring the oxygen concentration and skin temperature and potentially use that data as well in trying to measure the quality of sleep. If you investigate in a smart watch/fit bit type device that claims to measure sleep stages, you can attempt to correlate the periods the device says you are in REM with what you see in the flow rate data recorded by your APAP.
  • The 2/25 data shows a cluster of OA events start at 4:55 AM despite being near my max pressure already. Any advice on if anything should be done to control events like this?
Here's a screen shot of that cluster with a moderately zoomed in view:

Image

I'll first observe that this cluster happens about 3 hours after you turn the machine back on and go back to sleep after your family woke you up for a non-therapy related reason. That timing (3 hours after going to sleep) points to this cluster of events as quite probably being REM related.

And unfortunately, the fact that your machine was not allowed to raise the pressure beyond 12cm on this night, means that once you hit REM and your apnea got really bad, the machine was not able to respond by increasing the pressure to a level that would splint your airway open and allow you to keep breathing.
  • Is my flow limit at all an issue that something should be done about?
In zooming in on some random areas in your data that have been flagged as "flow limited"---i.e. that correspond to high areas on the flow limitation graph---my conclusion is that you do in fact have some real flow limitations that are likely indicative of your airway not being "stable" and in danger of collapsing. Moreover, many of these severe flow limitations occur when your pressure is at or near the max pressure setting of 12 cm or 13 cm indicates that you may need more pressure at some points in the night in order to give your airway the support it needs.

It is also worth pointing out that very often when your pressure drops to close to your current min pressure setting of 8cm, the flow limitations start. This indicates that you might want to bump your minimum pressure up a bit.

In other words, you might do better using a range of 9cm-14cm than you are doing with 8cm-13cm. If you really are struggling when the pressure gets above 13cm, you might want to try a range of 10cm-13cm.

Good luck!
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Respirator99
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Re: Data Analysis & High Respiratory Rate

Post by Respirator99 » Mon Feb 27, 2023 10:32 pm

While Oscar shows a respiratory rate graph, SleepHQ does not.
Actually, SleepHQ DOES show respiration rate. Depending on your preferences it might be under Advanced Charts.

The OP's chart is showing rates up to 50 bpm for extended periods every night. Zooming in shows a complex pattern of breath which does not look at all normal. I have seen this before but can't recall the cause.

https://www.dropbox.com/s/2rveyjkl6glku ... e.PNG?dl=0
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 2:39 am

Soft palate expiratory interference.
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Re: Data Analysis & High Respiratory Rate

Post by Respirator99 » Tue Feb 28, 2023 2:44 am

Rubicon wrote:
Tue Feb 28, 2023 2:39 am
Soft palate expiratory interference.
Thank you. So what's the solution? More pressure? Something else?
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 2:50 am

Respirator99 wrote:
Tue Feb 28, 2023 2:44 am
Rubicon wrote:
Tue Feb 28, 2023 2:39 am
Soft palate expiratory interference.
Thank you. So what's the solution? More pressure? Something else?
What, you slumming today?

I guess your boss didn't think that photo was as funny as we did, huh?
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 2:55 am

luciferin wrote:
Mon Feb 27, 2023 3:08 pm
...the high respiratory rate moments that I associate with REM sleep. I have tried 8 CPAP mode and I also never see the elevated REM and I feel noticeably worse.
It does look like there's a REM/EFL association there, but I can't believe that mess gives you quality sleep. so IMO 8.0 creates another problem. Have to see that record before tossing out WAGs.
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 3:16 am

Respirator99 wrote:
Tue Feb 28, 2023 2:44 am
Rubicon wrote:
Tue Feb 28, 2023 2:39 am
Soft palate expiratory interference.
Thank you. So what's the solution? More pressure? Something else?
Paul Fisher wrote:I have seen this pattern before but I can't recall what causes it. Somebody has posted something very similar on another forum so I'm following that to see if they come up with an explanation.
I'm going to need to charge you for the consult tho.
Last edited by Rubicon on Wed Mar 01, 2023 4:38 am, edited 1 time in total.
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 3:21 am

Besides. I already told Antoine what the issue was in one of my other personas:
Anyway, if you look at your waveforms go to Advanced and Respiratory Rate. Wherever you see an elevated RR, look up at the Flow Rate and you'll see that big ol' floppy palate getting in the way of your exhalation. My theory is that you leak and exhale through your mouth because that's the only place to exhale! Consider what happens if you tape your mouth shut.
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 3:40 am

Carol Dadswell wrote:Hi again Allan, I've now found the SleepHQ thread I mentioned, it was in response to a post by John Waters, in which Uncle Nicko included a flow pattern that I think looks similar to your zoomed in segment. Nicko suggested that this might be when some air goes into the stomach instead of the lungs. If you do search for 'aerophagia flow trace' you will be able to find it.
But hey, I'm open-minded. Ask your boy to explain the physiology behind his theory. Are those patients swallowing and immediately regurgitating 400 ml. of air (because the breath isn't lost in the waveform) once every 1.2 seconds?
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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 4:06 am

Oh-oh.

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Re: Data Analysis & High Respiratory Rate

Post by luciferin » Tue Feb 28, 2023 5:28 am

Someone on another forum suggested I try EPR, so I did that last night. Here are the results from that for what they're worth. I woke up more frequently than I have been without EPR. I woke from a dream at 5:15 AM, it was a bad one in the end. Would that likely be associated with the breathing issues that are evident starting around 5:04?

I looked back through the past month. A night that looked better was on nasal pillows. I do not do well with nasal only masks. I suffer mouth leak. If I mouth tape it gets blown off / I wake up with spit covering my face anyway.

Here's some screenshots of some OSCAR data from December where I actually slept a full night without the wild respiratory rate. Let me know if zooms of anything in particular would help. I appear to have had pretty high leaks that night. Could those just be masking the issue?

Screen shots from a date in November that I slept through the night with the full face mask and didn't have the expiratory interference. I included a zoom of an event that raised my pressure, and a 2nd zoom of some even that woke me from my sleep and made me take off the mask. I don't know why this was a good night. I had the exact same settings the night before and saw the pattern then.

Are there any recommendations? Is my pressure too high? Would it be better if I just mouth breathe all night?
This may seem odd, but could lower humidity help with this at all? I have always always slept better with lower humidity despite waking with a dry mouth, but I assumed it was anecdotal and just adjusted to my comfort, not my charts.
Last edited by luciferin on Tue Feb 28, 2023 6:44 am, edited 1 time in total.

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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 6:42 am

luciferin wrote:
Tue Feb 28, 2023 5:28 am
Someone on another forum suggested I try EPR...
It sounds like he was talking about some FL tho, not the high RR.

The PI certainly comes and goes, perhaps body position is the trigger.

IIWY rather than playing around in the dark I'd go see a good ENT before I got another titration and ask specifically "I think this palate is really screwing my sleep, how much for a trim?"

You could try nasal stents but they're like a Covid Test done with a fork.

In one of your D/Ls a high respiratory rate looks valid (hyperventilation).

Consider setting up an all-night camera to check body position and try to differentiate palate interference vs hyperventilation.
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Re: Data Analysis & High Respiratory Rate

Post by luciferin » Tue Feb 28, 2023 6:51 am

Rubicon wrote:
Tue Feb 28, 2023 6:42 am
It sounds like he was talking about some FL tho, not the high RR.
Thank you! They were talking about flow limits. It's hit or miss finding someone who actually looks at the whole picture online, you're the first person to actually look at my charts and see the RR I'm asking about.
Rubicon wrote:
Tue Feb 28, 2023 6:42 am
IIWY rather than playing around in the dark I'd go see a good ENT before I got another titration and ask specifically "I think this palate is really screwing my sleep, how much for a trim?"
I'll get an ENT visit set up through my PCP right away. I know I have an enlarged tonsil, and I'll ask him about the soft palate and everything else. Hopefully he can do some imaging and make some proper suggestions. I think I have a deviated septum, too, but no doctor has ever actually mentioned it to me as a problem. I really appreciate the advice, I am wicked tired of playing around in the dark.

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Re: Data Analysis & High Respiratory Rate

Post by Rubicon » Tue Feb 28, 2023 6:54 am

Tell 'em you need a DISE.
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