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Please let us know what you think of armodafinil. I haven't tried that variant.

isaacsmith wrote:One week later and my average AHI is down to 1.71! Thanks everyone for the advice, I can tell an improvement in my asthma and sleep quality.

I still feel fatigued though, either it'll take time for CPAP to help or something else is the cause.

nicholasjh1 wrote:Also no matter how good my therapy got I just felt fatigued during the day. Going on Modafinil for a while has helped some people go back to normal daytime functioning. So far it's been great for me. With my ADD, and general "rest seeking tendencies" that I think I picked up from having Apnea for so long, it's like the perfect anti-depressant for me (note it's not actually an anti-depressant, but it is known to raise Seritonin and dopamine levels. ). It's an "awake" promoter that is now on-label for CPAP users.

Huh, hadn't heard of that one before. I've been hesitant to use stimulants, but Modafinil's effects look like a great counteraction to fatigue. I'll look into it, thanks.

Your treatment may still not be optimized. Please post your latest data.

isaacsmith wrote:
Thanks both of you for sharing your experiences, I'll be trying armodafinil (a modafinil variant) in a few days. Hoping I get good results as well!

I've not tried the armodafinil, but it's supposed to have an even longer half-life than regular modafinil. I get a good 12 hrs boost from it, and I've heard the armodafinil can last as long as 14-16 hrs with some people. I would definitely recommend taking it as soon as you wake up until you know how long it's going to affect you. Don't want it to have the opposite effect and give you insomnia. Let us know how it goes!

Sunnymuffins wrote:I've not tried the armodafinil, but it's supposed to have an even longer half-life than regular modafinil. I get a good 12 hrs boost from it, and I've heard the armodafinil can last as long as 14-16 hrs with some people. I would definitely recommend taking it as soon as you wake up until you know how long it's going to affect you. Don't want it to have the opposite effect and give you insomnia. Let us know how it goes!

Yesterday was my first day using armodafinil. I took 150mg right after waking up. It took a bit over an hour before I started noticing the effects, the first thing I noticed was feeling warm and slightly itchy. Both of those subsided after a few minutes and I started to feel a bit more alert and focused, and a bit jittery. The effect slowly increased over the next few hours. Unfortunately, I still felt somewhat fatigued throughout the day, although much more focused and motivated than usual. I had a mild headache most of the day, although that's pretty common for me due to sinus issues. The effects tapered off faster than I expected, ten hours in and I was feeling close to my usual unfocused self. I didn't have any trouble falling or staying asleep.

I had a pretty productive day while on armodafinil, it was a day off from work but I made quite a bit of progress on a hobby project. I tend to get lost in thought easily due to fatigue, but armodafinil helped me stay on track.

Just took my day-2 dose a couple hours ago, I'm interested if the effect will be similar or stronger on the second dose. I'm taking it with my usual liter of coffee today (I forewent it yesterday to feel armodafinil's effects in isolation). So far the onset seems even milder than yesterday, but I can definitely feel the effects kick in as I write this.

Back to the subject of sleep apnea, my weekly average AHI is at 2.72 now. The worst night in that week was an AHI of 4.08, here's the chart:



I'm still having considerably more CAs than obstructives. Also, that seems to be quite a lot of vibratory snore events, I seem to have similar numbers of those every night both before and after I upped the pressure.

Last night's after-armodafinil sleep was similar: AHI of 3.82, this time evenly divided between CAs, hypopneas, and obstructives.



Should I keep bumping up the pressure? Or is there some other way I can improve my sleep?

Increasing the pressure won't reduce the number of centrals/clear airway apneas.