General Discussion on any topic relating to CPAP and/or Sleep Apnea.
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sleepstar
- Posts: 442
- Joined: Wed Jan 16, 2013 4:46 am
- Location: London, UK
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by sleepstar » Wed Apr 20, 2016 7:36 am
ChicagoGranny wrote:sleepstar wrote:There's no treatment in a pill.
You are overlooking the fact that there is often in OSA patients below-normal upper-airway motor neuron activity. If a drug is available that improves upper-airway motor neuron activity, OSA could be improved.
For now, no effective drug is available. Only electrical stimulation devices are available, such as
http://www.inspiresleep.com/what-is-ins ... apy-works/ .
The electrical stimulation developments are exciting. My lab has been involved in them and I found it very interesting. Unfortunately one of the companies went bust. I do hope that we see these further developing - especially for people who can't tolerate CPAP.
Although I don't use CPAP myself, I think I can sympathise with those who have difficulty with it. For example, I should wear a splint each night because I'm grinding my teeth terribly. Despite being in dental school and KNOWING the benefit, you think I can wear it each night? I struggle. So I really look forward to seeing more developments in sleep medicine.
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Sir NoddinOff
- Posts: 4190
- Joined: Mon May 14, 2012 5:30 pm
- Location: California
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by Sir NoddinOff » Wed Apr 20, 2016 12:43 pm
I can't imagine that Mirtazapine would have any application in lowering AHI. For a short while I tried Mirtazapine as a sleep aid (a year and a half ago). It really did nothing to help me get to sleep or stay asleep. About that time, my sleep doctor mentioned that it is was primarily an antidepressant med that didn't interfere with one's sleep or sleep structure, also it didn't create insomnia as a side-effect, unlike so many SSRI and tricyclic antidepressants. It's been discussed here a lot over the years... simply type Remeron or Mirtazapine in the search window below the CPAPtalk logo.
I like my ResMed AirFit F10 FFM - reasonably low leaks for my ASV therapy. I'm currently using a PR S1 AutoSV 960P Advanced. I also keep a ResMed S9 Adapt as backup. I use a heated Hibernite hose. Still rockin' with Win 7 by using GWX to stop Win 10.
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Menlodoc
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by Menlodoc » Wed Jun 08, 2016 12:28 am
I am a physician and have taken Remeron, 15 mg nightly for the last 10 years. I also use a dental appliance. THe appliance by itself reduces my AHI from 37 to about 16. When Remeron is added, I get a further reduction so my AHI is only 7-8. Most physicians are unfamiliar with the literature regarding Remeron and physicians who treat sleep disorders don't like Remeron because it can cause weight gain, which can make sleep apnea worse. I am thin and thus this side effect is not a problem for me.
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ChicagoGranny
- Posts: 14855
- Joined: Sun Jan 29, 2012 1:43 pm
- Location: USA
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by ChicagoGranny » Wed Jun 08, 2016 6:15 am
Menlodoc wrote:my AHI is only 7-8
That's not good enough for CPAPTALKers.
If you sleep 7 hours, and your AHI is 7, then you are awoken 49 times during the night. This is a very unhealthy condition.
Use CPAP.