The absolute best in my opinion would be the Resmed S8 II AutoSet. The new EasyBreathe technology is smooth and great. EPR is available in straight CPAP mode or in auto mode. The integrated humidifier is EASY to install and fill and clean. There's quite a bit of data available w/an easy button push combo via the LCD screen. It is lightweight and quiet.
The Resmed S8 II Elite w/EPR is the best straight CPAP available, again in my opinion, and is the equivalent of the AutoSet w/o the auto mode.
Many here swear by the Respironics M Series Auto w/A-Flex. There is also a Respironics M Series Auto w/C-Flex. In straight CPAP it would be the Respironics M Series Pro w/C-Flex.
The most devoted fans seem to be the minority who have the Puritan Bennett GoodKnight 420E. I've never heard a complaint against this device. And, PB (now Covidian) has come out w/the new Sandman Info (straight CPAP) and Sandman Auto. If you NEED exhalation pressure relief the PB/Covidians don't provide it. But the users say that it really isn't needed w/these devices.
Any of the above xPAPs would be a good choice. All are top quality devices. cpap.com allows you to do a comparison of the devices that interest you by category (CPAP & autoPAP) and you can print out the comparisons to mull over more than once.
One thing to keep in mind: Resmed, Respironics and Fisher & Paykel have somewhat recently instituted MAP (minimum advertised pricing) policies against online DME suppliers so you can't "believe" the prices posted for these brands' devices. Decide which interest you and then call the online supplier via their toll-free number and ASK if they have an "unadvertised sale price" on it/them. The MAPs make online price comparison shopping a bit more difficult but it can be done w/o too great an effort.
Women are Angels. And when someone breaks our wings, we simply continue to fly.....on a broomstick. We are flexible like that.
My computer says I need to upgrade my brain to be compatible with its new software.